Lck, membrane microdomains and TCR triggering machinery: defining the new rules of engagement

Lck, membrane microdomains and TCR triggering machinery: defining the new rules of engagement

In spite of a comprehensive understanding of the schematics of T cell receptor (TCR) signaling, the mechanisms regulating compartmentalization of signaling molecules, their transient interactions and rearrangement of membrane structures initiated upon TCR engagement remain an outstanding problem. Th...

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Bibliographic Details
Main Authors: Dominik eFilipp, Ondřej eBallek, Jasper eManning
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Immunology
Subjects:
Membrane Microdomains
compartmentalization
Fyn
Lck
heavy and light DRMs
TCR triggering
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00155/full

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