Metabolomics-transcriptomics joint analysis: unveiling the dysregulated cell death network and developing a diagnostic model for high-grade neuroblastoma

Metabolomics-transcriptomics joint analysis: unveiling the dysregulated cell death network and developing a diagnostic model for high-grade neuroblastoma

High-grade neuroblastoma (HG-NB) exhibits a significantly diminished survival rate in comparison to low-grade neuroblastoma (LG-NB), primarily attributed to the mechanism of HG-NB is unclear and the lacking effective therapeutic targets and diagnostic model. Therefore, the current investigation aims...

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Bibliographic Details
Main Authors: Wancun Zhang, Mengxin Zhang, Meng Sun, Minghui Hu, Muchun Yu, Jushan Sun, Xianwei Zhang, Bang Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
neuroblastoma
metabolomics
transcriptomics; therapeutic target
network
diagnostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1345734/full

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