Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial
Background: Evidence supports a causal relationship between circadian disturbance and impaired glucose homeostasis. Methods: To determine the effect of an educational intervention delivered by primary care nurses to improve sleep hygiene, a parallel, open-label clinical trial in subjects aged 18 and...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Online Access: | https://www.mdpi.com/2079-7737/11/6/893 |
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| author | Cristina García-Serrano Jesús Pujol Salud Lidia Aran-Solé Joaquim Sol Sònia Ortiz-Congost Eva Artigues-Barberà Marta Ortega-Bravo |
| author_facet | Cristina García-Serrano Jesús Pujol Salud Lidia Aran-Solé Joaquim Sol Sònia Ortiz-Congost Eva Artigues-Barberà Marta Ortega-Bravo |
| author_sort | Cristina García-Serrano |
| collection | DOAJ |
| description | Background: Evidence supports a causal relationship between circadian disturbance and impaired glucose homeostasis. Methods: To determine the effect of an educational intervention delivered by primary care nurses to improve sleep hygiene, a parallel, open-label clinical trial in subjects aged 18 and older with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2DM) was performed. Study variables were sex, age, fasting glucose, glycated haemoglobin A1c (HbA1c), Pittsburgh Sleep Quality Index (PSQI), sleep duration and efficiency, body mass index, antidiabetic treatment, diet and physical exercise. An individual informative educational intervention was carried out following a bidirectional feedback method. The intervention aimed to develop skills to improve sleep through nine simple tips. An analysis of covariance was performed on all the mean centred outcome variables controlling for the respective baseline scores. Results: In the intervention group, PSQI dropped, the duration and quality of sleep increased, and a decrease in fasting glucose and in HbA1c levels was observed. Conclusion: The proposed intervention is effective for improving sleep quality, length and efficiency, and for decreasing fasting glucose and HbA1c levels in only 3 months. These findings support the importance of sleep and circadian rhythm education focused on improving IFG and T2DM. |
| first_indexed | 2024-03-10T00:22:44Z |
| format | Article |
| id | doaj.art-5e982d3e622046008aa2f7fe0b995263 |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-10T00:22:44Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-5e982d3e622046008aa2f7fe0b9952632023-11-23T15:40:02ZengMDPI AGBiology2079-77372022-06-0111689310.3390/biology11060893Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled TrialCristina García-Serrano0Jesús Pujol Salud1Lidia Aran-Solé2Joaquim Sol3Sònia Ortiz-Congost4Eva Artigues-Barberà5Marta Ortega-Bravo6Balaguer Primary Care Centre, Institut Català de la Salut (ICS), 25600 Lleida, SpainBalaguer Primary Care Centre, Institut Català de la Salut (ICS), 25600 Lleida, SpainBalaguer Primary Care Centre, Institut Català de la Salut (ICS), 25600 Lleida, SpainCatalan Health Institute (ICS), Primary Care Lleida, Rambla Ferran, 44, 25007 Lleida, SpainBalaguer Primary Care Centre, Institut Català de la Salut (ICS), 25600 Lleida, SpainResearch Group in Therapies in Primary Care (GRETAPS), Fundació Institut Universitari per a la Recerca en Atenció Primària de Salut Jordi Gol i Gurina (IDIAP JGol), 25007 Lleida, SpainResearch Group in Therapies in Primary Care (GRETAPS), Fundació Institut Universitari per a la Recerca en Atenció Primària de Salut Jordi Gol i Gurina (IDIAP JGol), 25007 Lleida, SpainBackground: Evidence supports a causal relationship between circadian disturbance and impaired glucose homeostasis. Methods: To determine the effect of an educational intervention delivered by primary care nurses to improve sleep hygiene, a parallel, open-label clinical trial in subjects aged 18 and older with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2DM) was performed. Study variables were sex, age, fasting glucose, glycated haemoglobin A1c (HbA1c), Pittsburgh Sleep Quality Index (PSQI), sleep duration and efficiency, body mass index, antidiabetic treatment, diet and physical exercise. An individual informative educational intervention was carried out following a bidirectional feedback method. The intervention aimed to develop skills to improve sleep through nine simple tips. An analysis of covariance was performed on all the mean centred outcome variables controlling for the respective baseline scores. Results: In the intervention group, PSQI dropped, the duration and quality of sleep increased, and a decrease in fasting glucose and in HbA1c levels was observed. Conclusion: The proposed intervention is effective for improving sleep quality, length and efficiency, and for decreasing fasting glucose and HbA1c levels in only 3 months. These findings support the importance of sleep and circadian rhythm education focused on improving IFG and T2DM.https://www.mdpi.com/2079-7737/11/6/893glucose metabolism disorderscircadian rhythmsleepblood glucoseglycated haemoglobin A1c |
| spellingShingle | Cristina García-Serrano Jesús Pujol Salud Lidia Aran-Solé Joaquim Sol Sònia Ortiz-Congost Eva Artigues-Barberà Marta Ortega-Bravo Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial Biology glucose metabolism disorders circadian rhythm sleep blood glucose glycated haemoglobin A1c |
| title | Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial |
| title_full | Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial |
| title_fullStr | Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial |
| title_full_unstemmed | Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial |
| title_short | Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial |
| title_sort | enhancing night and day circadian contrast through sleep education in prediabetes and type 2 diabetes mellitus a randomized controlled trial |
| topic | glucose metabolism disorders circadian rhythm sleep blood glucose glycated haemoglobin A1c |
| url | https://www.mdpi.com/2079-7737/11/6/893 |
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