Effects of <i>SLCO1B1</i> Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment

Effects of <i>SLCO1B1</i> Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment

Organic-anion-transporting polypeptide 1B1 (OATP1B1), encoded by the solute carrier organic anion transporter family member 1B1 gene (<i>SLCO1B1</i>), is highly expressed in the liver and transports several endogenous metabolites into the liver, including statins. Previous studies have n...

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Bibliographic Details
Main Authors: Lilian Fernandes Silva, Rowmika Ravi, Jagadish Vangipurapu, Anniina Oravilahti, Markku Laakso
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
SLCO1B
OATP1B1
simvastatin
metabolomics
metabolites
Online Access:https://www.mdpi.com/2218-1989/12/12/1159

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