Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury

Abstract Promoting bone healing including fracture non-unions are promising targets for bone tissue engineering due to the limited success of current clinical treatment methods. There has been significant research on the use of stem cells with and without biomaterial scaffolds to treat bone fracture...

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Bibliographic Details
Main Authors: Leah Ferrie, Priyatha Premnath, Alexandra Olsen, Leila Larijani, Bryce A. Besler, Derrick E. Rancourt, Neil A. Duncan, T. Michael Underhill, Roman J. Krawetz
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36609-z