Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence
Palm oil/olein (PO/POL) is used in infant formulas to imitate the fatty acid profile of human milk (HM) and achieve similar levels of palmitic acid (PA). However, the positions of fatty acids on the triacylglyceride differ between PO/POL and HM, which affect fat absorption and produce unintended phy...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-11-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/12/12/3676 |
| _version_ | 1797546392742264832 |
|---|---|
| author | Maria Padial-Jaudenes Esther Castanys-Munoz Maria Ramirez John Lasekan |
| author_facet | Maria Padial-Jaudenes Esther Castanys-Munoz Maria Ramirez John Lasekan |
| author_sort | Maria Padial-Jaudenes |
| collection | DOAJ |
| description | Palm oil/olein (PO/POL) is used in infant formulas to imitate the fatty acid profile of human milk (HM) and achieve similar levels of palmitic acid (PA). However, the positions of fatty acids on the triacylglyceride differ between PO/POL and HM, which affect fat absorption and produce unintended physiological consequences. Recent papers have reviewed evidence for physiological benefits of PO/POL and beta-palmitate (sn-2-palmitate) in infant formulas. The aim of the present review is to supplement the assessment of available clinical evidence on the physiological effects of PO/POL formulas in healthy infants. We intend to focus on PO/POL and not on sn-2-palmitate, since the latter was recently extensively reviewed. Clinical evidence supports that PO/POL in infant formulas leads to a lower fat, DHA, palmitate and calcium absorption, and bone mineralization; soft stools; and growth (weight accretion) compared to formulas without PO/POL. Consequently, it seems prudent to be considerate and cautious when adding PO/POL to infant formulas. While HM is the gold standard for infant nutrition, the development of infant formula should be based on achieving positive physiological outcomes, rather than just replicating HM nutrient composition. |
| first_indexed | 2024-03-10T14:29:07Z |
| format | Article |
| id | doaj.art-5e9e9a0b0ab94e288c654b2e14a90e82 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T14:29:07Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-5e9e9a0b0ab94e288c654b2e14a90e822023-11-20T22:46:26ZengMDPI AGNutrients2072-66432020-11-011212367610.3390/nu12123676Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical EvidenceMaria Padial-Jaudenes0Esther Castanys-Munoz1Maria Ramirez2John Lasekan3Abbott Nutrition R&D, Granada University Science Park, 18016 Granada, SpainAbbott Nutrition R&D, Granada University Science Park, 18016 Granada, SpainAbbott Nutrition R&D, Abbott Laboratories, 18004 Granada, SpainScientific & Medical Affairs, Abbott Nutrition, Abbott Laboratories, Columbus, OH 43219, USAPalm oil/olein (PO/POL) is used in infant formulas to imitate the fatty acid profile of human milk (HM) and achieve similar levels of palmitic acid (PA). However, the positions of fatty acids on the triacylglyceride differ between PO/POL and HM, which affect fat absorption and produce unintended physiological consequences. Recent papers have reviewed evidence for physiological benefits of PO/POL and beta-palmitate (sn-2-palmitate) in infant formulas. The aim of the present review is to supplement the assessment of available clinical evidence on the physiological effects of PO/POL formulas in healthy infants. We intend to focus on PO/POL and not on sn-2-palmitate, since the latter was recently extensively reviewed. Clinical evidence supports that PO/POL in infant formulas leads to a lower fat, DHA, palmitate and calcium absorption, and bone mineralization; soft stools; and growth (weight accretion) compared to formulas without PO/POL. Consequently, it seems prudent to be considerate and cautious when adding PO/POL to infant formulas. While HM is the gold standard for infant nutrition, the development of infant formula should be based on achieving positive physiological outcomes, rather than just replicating HM nutrient composition.https://www.mdpi.com/2072-6643/12/12/3676palm oleininfant formulascalcium absorptionfat absorptionDHA absorptionbone mineralization |
| spellingShingle | Maria Padial-Jaudenes Esther Castanys-Munoz Maria Ramirez John Lasekan Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence Nutrients palm olein infant formulas calcium absorption fat absorption DHA absorption bone mineralization |
| title | Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence |
| title_full | Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence |
| title_fullStr | Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence |
| title_full_unstemmed | Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence |
| title_short | Physiological Impact of Palm Olein or Palm Oil in Infant Formulas: A Review of Clinical Evidence |
| title_sort | physiological impact of palm olein or palm oil in infant formulas a review of clinical evidence |
| topic | palm olein infant formulas calcium absorption fat absorption DHA absorption bone mineralization |
| url | https://www.mdpi.com/2072-6643/12/12/3676 |
| work_keys_str_mv | AT mariapadialjaudenes physiologicalimpactofpalmoleinorpalmoilininfantformulasareviewofclinicalevidence AT esthercastanysmunoz physiologicalimpactofpalmoleinorpalmoilininfantformulasareviewofclinicalevidence AT mariaramirez physiologicalimpactofpalmoleinorpalmoilininfantformulasareviewofclinicalevidence AT johnlasekan physiologicalimpactofpalmoleinorpalmoilininfantformulasareviewofclinicalevidence |