Hydrophilic and Functionalized Nanographene Oxide Incorporated Faster Dissolving Megestrol Acetate

Hydrophilic and Functionalized Nanographene Oxide Incorporated Faster Dissolving Megestrol Acetate

The aim of this work is to present an approach to enhance the dissolution of progestin medication, megestrol acetate (also known as MEGACE), for improving the dissolution rate and kinetic solubility by incorporating nano graphene oxide (nGO). An antisolvent precipitation process was investigated for...

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Bibliographic Details
Main Authors: Mohammad Saiful Islam, Faradae Renner, Kimberly Foster, Martin S. Oderinde, Kevin Stefanski, Somenath Mitra
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
enhanced dissolution
nano graphene oxide
oral medication
paddle method
gastrointestinal pH
megestrol acetate
Online Access:https://www.mdpi.com/1420-3049/26/7/1972

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