Electrostatic interactions guide substrate recognition of the prokaryotic ubiquitin-like protein ligase PafA

Abstract Pupylation, a post-translational modification found in Mycobacterium tuberculosis and other Actinobacteria, involves the covalent attachment of prokaryotic ubiquitin-like protein (Pup) to lysines on target proteins by the ligase PafA (proteasome accessory factor A). Pupylated proteins, like...

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Бібліографічні деталі
Автори: Matthias F. Block, Cyrille L. Delley, Lena M. L. Keller, Timo T. Stuehlinger, Eilika Weber-Ban
Формат: Стаття
Мова:English
Опубліковано: Nature Portfolio 2023-08-01
Серія:Nature Communications
Онлайн доступ:https://doi.org/10.1038/s41467-023-40807-8