Electrostatic interactions guide substrate recognition of the prokaryotic ubiquitin-like protein ligase PafA
Abstract Pupylation, a post-translational modification found in Mycobacterium tuberculosis and other Actinobacteria, involves the covalent attachment of prokaryotic ubiquitin-like protein (Pup) to lysines on target proteins by the ligase PafA (proteasome accessory factor A). Pupylated proteins, like...
Автори: | , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Nature Portfolio
2023-08-01
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Серія: | Nature Communications |
Онлайн доступ: | https://doi.org/10.1038/s41467-023-40807-8 |