Importance of the PD-1/PD-L1 Axis for Malignant Transformation and Risk Assessment of Oral Leukoplakia

Importance of the PD-1/PD-L1 Axis for Malignant Transformation and Risk Assessment of Oral Leukoplakia

Background: The programmed cell death ligand 1/programmed cell death receptor 1 (PD-L1/PD-1) Immune Checkpoint is an important modulator of the immune response. Overexpression of the receptor and its ligands is involved in immunosuppression and the failure of an immune response against tumor cells....

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Bibliografske podrobnosti
Main Authors: Jutta Ries, Abbas Agaimy, Falk Wehrhan, Christoph Baran, Stella Bolze, Eva Danzer, Silke Frey, Jonathan Jantsch, Tobias Möst, Maike Büttner-Herold, Claudia Wickenhauser, Marco Kesting, Manuel Weber
Format: Article
Jezik:English
Izdano: MDPI AG 2021-02-01
Serija:Biomedicines
Teme:
immune checkpoints
PD-1
PD-L1
oral leukoplakia
OSCC
malignant transformation
Online dostop:https://www.mdpi.com/2227-9059/9/2/194

Internet

https://www.mdpi.com/2227-9059/9/2/194

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