Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare
Animal welfare is recognized as essential for the coexistence of humans and animals. Considering the increased demand and interest in animal welfare, many methods for improving animal welfare are being devised, but which method reduces animal stress has not been scientifically verified. Therefore, r...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/2/249 |
| _version_ | 1827629336087232512 |
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| author | Gwang-Hoon Lee KilSoo Kim Woori Jo |
| author_facet | Gwang-Hoon Lee KilSoo Kim Woori Jo |
| author_sort | Gwang-Hoon Lee |
| collection | DOAJ |
| description | Animal welfare is recognized as essential for the coexistence of humans and animals. Considering the increased demand and interest in animal welfare, many methods for improving animal welfare are being devised, but which method reduces animal stress has not been scientifically verified. Therefore, reducing animal stress by providing a proper breeding environment and environmental enrichment can be the basis for animal study. In this study, stress levels were assessed based on the mouse-breeding environment. We considered that the higher the body weight and the lower the corticosterone concentration, the lower the stress. According to the results, animals in the individual ventilation cages were determined to have lower serum cortisol concentrations, while the body weight of the animals was increased when in individual ventilation cages compared with individual isolated cages and when providing environmental enrichment compared with group breeding or not providing environmental enrichment. The results provide appropriate guidelines for improving laboratory animal welfare. |
| first_indexed | 2024-03-09T13:49:03Z |
| format | Article |
| id | doaj.art-5ea638cfd1884a508c5ed2c9296c182f |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T13:49:03Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-5ea638cfd1884a508c5ed2c9296c182f2023-11-30T20:53:17ZengMDPI AGAnimals2076-26152023-01-0113224910.3390/ani13020249Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal WelfareGwang-Hoon Lee0KilSoo Kim1Woori Jo2Preclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of KoreaPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of KoreaPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of KoreaAnimal welfare is recognized as essential for the coexistence of humans and animals. Considering the increased demand and interest in animal welfare, many methods for improving animal welfare are being devised, but which method reduces animal stress has not been scientifically verified. Therefore, reducing animal stress by providing a proper breeding environment and environmental enrichment can be the basis for animal study. In this study, stress levels were assessed based on the mouse-breeding environment. We considered that the higher the body weight and the lower the corticosterone concentration, the lower the stress. According to the results, animals in the individual ventilation cages were determined to have lower serum cortisol concentrations, while the body weight of the animals was increased when in individual ventilation cages compared with individual isolated cages and when providing environmental enrichment compared with group breeding or not providing environmental enrichment. The results provide appropriate guidelines for improving laboratory animal welfare.https://www.mdpi.com/2076-2615/13/2/249animal welfareenvironmental enrichmenthousinglaboratory animalsstress evaluation |
| spellingShingle | Gwang-Hoon Lee KilSoo Kim Woori Jo Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare Animals animal welfare environmental enrichment housing laboratory animals stress evaluation |
| title | Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare |
| title_full | Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare |
| title_fullStr | Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare |
| title_full_unstemmed | Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare |
| title_short | Stress Evaluation of Mouse Husbandry Environments for Improving Laboratory Animal Welfare |
| title_sort | stress evaluation of mouse husbandry environments for improving laboratory animal welfare |
| topic | animal welfare environmental enrichment housing laboratory animals stress evaluation |
| url | https://www.mdpi.com/2076-2615/13/2/249 |
| work_keys_str_mv | AT gwanghoonlee stressevaluationofmousehusbandryenvironmentsforimprovinglaboratoryanimalwelfare AT kilsookim stressevaluationofmousehusbandryenvironmentsforimprovinglaboratoryanimalwelfare AT woorijo stressevaluationofmousehusbandryenvironmentsforimprovinglaboratoryanimalwelfare |