Procalcitonin elevation induced by sympathomimetic drug overdose
Background Procalcitonin, a biomarker used to detect systemic bacterial infection, can be elevated in other conditions. Some case reports have suggested procalcitonin elevation induced by drug overdose. Case Presentation A 20‐year‐old woman with insignificant medical history presented with vomiting,...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Acute Medicine & Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ams2.687 |
| _version_ | 1819094087409598464 |
|---|---|
| author | Sota Kodama Masahiro Kashiura Takashi Moriya |
| author_facet | Sota Kodama Masahiro Kashiura Takashi Moriya |
| author_sort | Sota Kodama |
| collection | DOAJ |
| description | Background Procalcitonin, a biomarker used to detect systemic bacterial infection, can be elevated in other conditions. Some case reports have suggested procalcitonin elevation induced by drug overdose. Case Presentation A 20‐year‐old woman with insignificant medical history presented with vomiting, fever, and impaired consciousness. Her vital signs showed an altered mental status (Glasgow Coma Scale score, 11 [E4V1M6]) and high fever (38.0°C), and no significant neurological signs were detected. Laboratory tests revealed that her serum procalcitonin level was significantly high (>10 ng/dL). Gradually, her level of consciousness improved, and she admitted that she had taken an overdose of sympathomimetic drugs. She was discharged from the hospital on day 5 without any problems. Conclusion Drug overdose is seldom mentioned as one of the causes of serum procalcitonin level elevation. Sympathomimetic drug overdose can be one of the causes of procalcitonin elevation. |
| first_indexed | 2024-12-21T23:21:50Z |
| format | Article |
| id | doaj.art-5ea67a590cbc4ddeaf3fc402f09a2aea |
| institution | Directory Open Access Journal |
| issn | 2052-8817 |
| language | English |
| last_indexed | 2024-12-21T23:21:50Z |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Acute Medicine & Surgery |
| spelling | doaj.art-5ea67a590cbc4ddeaf3fc402f09a2aea2022-12-21T18:46:47ZengWileyAcute Medicine & Surgery2052-88172021-01-0181n/an/a10.1002/ams2.687Procalcitonin elevation induced by sympathomimetic drug overdoseSota Kodama0Masahiro Kashiura1Takashi Moriya2Department of Emergency and Critical Care Medicine Saitama Medical Center Jichi Medical University Saitama JapanDepartment of Emergency and Critical Care Medicine Saitama Medical Center Jichi Medical University Saitama JapanDepartment of Emergency and Critical Care Medicine Saitama Medical Center Jichi Medical University Saitama JapanBackground Procalcitonin, a biomarker used to detect systemic bacterial infection, can be elevated in other conditions. Some case reports have suggested procalcitonin elevation induced by drug overdose. Case Presentation A 20‐year‐old woman with insignificant medical history presented with vomiting, fever, and impaired consciousness. Her vital signs showed an altered mental status (Glasgow Coma Scale score, 11 [E4V1M6]) and high fever (38.0°C), and no significant neurological signs were detected. Laboratory tests revealed that her serum procalcitonin level was significantly high (>10 ng/dL). Gradually, her level of consciousness improved, and she admitted that she had taken an overdose of sympathomimetic drugs. She was discharged from the hospital on day 5 without any problems. Conclusion Drug overdose is seldom mentioned as one of the causes of serum procalcitonin level elevation. Sympathomimetic drug overdose can be one of the causes of procalcitonin elevation.https://doi.org/10.1002/ams2.687Caffeinedrug overdoseephedrineprocalcitoninsympathomimetic drug |
| spellingShingle | Sota Kodama Masahiro Kashiura Takashi Moriya Procalcitonin elevation induced by sympathomimetic drug overdose Acute Medicine & Surgery Caffeine drug overdose ephedrine procalcitonin sympathomimetic drug |
| title | Procalcitonin elevation induced by sympathomimetic drug overdose |
| title_full | Procalcitonin elevation induced by sympathomimetic drug overdose |
| title_fullStr | Procalcitonin elevation induced by sympathomimetic drug overdose |
| title_full_unstemmed | Procalcitonin elevation induced by sympathomimetic drug overdose |
| title_short | Procalcitonin elevation induced by sympathomimetic drug overdose |
| title_sort | procalcitonin elevation induced by sympathomimetic drug overdose |
| topic | Caffeine drug overdose ephedrine procalcitonin sympathomimetic drug |
| url | https://doi.org/10.1002/ams2.687 |
| work_keys_str_mv | AT sotakodama procalcitoninelevationinducedbysympathomimeticdrugoverdose AT masahirokashiura procalcitoninelevationinducedbysympathomimeticdrugoverdose AT takashimoriya procalcitoninelevationinducedbysympathomimeticdrugoverdose |