Sevoflurane exposure induces neurotoxicity by regulating mitochondrial function of microglia due to NAD insufficiency
Developmental neurons received with sevoflurane, the commonly used inhalational anesthetic agent in clinical surgery, several times tend to be destroyed. Microglia, the resident immune cells of the central nervous system (CNS), are activated after sevoflurane exposure, accompanied by releasing proin...
Main Authors: | Ruilou Zhu, Shuang Zeng, Ningning Li, Ningning Fu, Yangyang Wang, Mengrong Miao, Yitian Yang, Mingyang Sun, Jiaqiang Zhang |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fncel.2022.914957/full |
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