Sevoflurane exposure induces neurotoxicity by regulating mitochondrial function of microglia due to NAD insufficiency

Sevoflurane exposure induces neurotoxicity by regulating mitochondrial function of microglia due to NAD insufficiency

Developmental neurons received with sevoflurane, the commonly used inhalational anesthetic agent in clinical surgery, several times tend to be destroyed. Microglia, the resident immune cells of the central nervous system (CNS), are activated after sevoflurane exposure, accompanied by releasing proin...

Full description

Bibliographic Details
Main Authors: Ruilou Zhu, Shuang Zeng, Ningning Li, Ningning Fu, Yangyang Wang, Mengrong Miao, Yitian Yang, Mingyang Sun, Jiaqiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
sevoflurane
neurotoxicity
microglia
mitochondria
NAD
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.914957/full

Similar Items

Similar Items