Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis

Mechanism Study of Thermally Induced Anti-Tumor Drug Loading to Engineered Human Heavy-Chain Ferritin Nanocages Aided by Computational Analysis

Diverse drug loading approaches for human heavy-chain ferritin (HFn), a promising drug nanocarrier, have been established. However, anti-tumor drug loading ratio and protein carrier recovery yield are bottlenecks for future clinical application. Mechanisms behind drug loading have not been elaborate...

Full description

Bibliographic Details
Main Authors: Shuang Yin, Yongdong Liu, Sheng Dai, Bingyang Zhang, Yiran Qu, Yao Zhang, Woo-Seok Choe, Jingxiu Bi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biosensors
Subjects:
ferritin
drug delivery
thermally induced drug loading
computational analysis
Online Access:https://www.mdpi.com/2079-6374/11/11/444

Similar Items

Similar Items