Thyroid Stimulating Hormone Resistance Syndrome – A Case Report

Resistance to thyrotropin or thyroid stimulating hormone (RTSH) can be defined as decreased responsiveness to thyroid stimulating hormone (TSH) characterized by high TSH with normal but occasionally low T4 and T3 usually in absence of goiter or ectopic thyroid. It can be diagnosed when TSH is >30...

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Main Authors: SM Ashrafuzzaman, Zafar A Latif
Format: Article
Language:English
Published: Ibrahim Medical College 2014-01-01
Series:IMC Journal of Medical Science
Subjects:
Online Access:http://www.imcjms.com/registration/journal_full_text/248
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author SM Ashrafuzzaman
Zafar A Latif
author_facet SM Ashrafuzzaman
Zafar A Latif
author_sort SM Ashrafuzzaman
collection DOAJ
description Resistance to thyrotropin or thyroid stimulating hormone (RTSH) can be defined as decreased responsiveness to thyroid stimulating hormone (TSH) characterized by high TSH with normal but occasionally low T4 and T3 usually in absence of goiter or ectopic thyroid. It can be diagnosed when TSH is >30 mIU/L but free T4 (FT4) is within normal limit. Patient usually presents in euthyroid state with abnormally high TSH but may also present with mild to overt hypothyroidism. The precise prevalence is not known, but 20-30% infants may show transient mild RTSH. In adults it is rare. Here we report a case of RTSH in which a 19 years old young girl presented in euthyroid state with mild goiter. Ibrahim Med. Coll. J. 2014; 8(1): 32-33
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spelling doaj.art-5ea90d9aa235465f82eaf3112e7d4ece2022-12-22T01:09:12ZengIbrahim Medical CollegeIMC Journal of Medical Science2519-17212519-15862014-01-01813233Thyroid Stimulating Hormone Resistance Syndrome – A Case ReportSM Ashrafuzzaman0Zafar A Latif1Department of Endocrinology,Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM),122, Kazi Nazrul Islam Avenue, Shahbagh, Dhaka-1000Department of Endocrinology,Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM),122, Kazi Nazrul Islam Avenue, Shahbagh, Dhaka-1000Resistance to thyrotropin or thyroid stimulating hormone (RTSH) can be defined as decreased responsiveness to thyroid stimulating hormone (TSH) characterized by high TSH with normal but occasionally low T4 and T3 usually in absence of goiter or ectopic thyroid. It can be diagnosed when TSH is >30 mIU/L but free T4 (FT4) is within normal limit. Patient usually presents in euthyroid state with abnormally high TSH but may also present with mild to overt hypothyroidism. The precise prevalence is not known, but 20-30% infants may show transient mild RTSH. In adults it is rare. Here we report a case of RTSH in which a 19 years old young girl presented in euthyroid state with mild goiter. Ibrahim Med. Coll. J. 2014; 8(1): 32-33http://www.imcjms.com/registration/journal_full_text/248Resistance syndromeTSHFT4
spellingShingle SM Ashrafuzzaman
Zafar A Latif
Thyroid Stimulating Hormone Resistance Syndrome – A Case Report
IMC Journal of Medical Science
Resistance syndrome
TSH
FT4
title Thyroid Stimulating Hormone Resistance Syndrome – A Case Report
title_full Thyroid Stimulating Hormone Resistance Syndrome – A Case Report
title_fullStr Thyroid Stimulating Hormone Resistance Syndrome – A Case Report
title_full_unstemmed Thyroid Stimulating Hormone Resistance Syndrome – A Case Report
title_short Thyroid Stimulating Hormone Resistance Syndrome – A Case Report
title_sort thyroid stimulating hormone resistance syndrome a case report
topic Resistance syndrome
TSH
FT4
url http://www.imcjms.com/registration/journal_full_text/248
work_keys_str_mv AT smashrafuzzaman thyroidstimulatinghormoneresistancesyndromeacasereport
AT zafaralatif thyroidstimulatinghormoneresistancesyndromeacasereport