Effect of mesenchymal stem cells on animal semen during storage
Mesenchymal stem cells (MSCs) have been known to mankind since the mid-20th century. The comprehensive study revealed their high biologically active potential. Capacity of forming several types of body tissues was demonstrated. The stem cells, like any other cells, exert their effect on surrounding c...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Da Vinci Media
2023-12-01
|
| Series: | Ветеринария сегодня |
| Subjects: | |
| Online Access: | https://veterinary.arriah.ru/jour/article/view/772 |
| _version_ | 1826812428394954752 |
|---|---|
| author | E. Yu. Zakirova A. G. Malanyeva A. M. Aimaletdinov |
| author_facet | E. Yu. Zakirova A. G. Malanyeva A. M. Aimaletdinov |
| author_sort | E. Yu. Zakirova |
| collection | DOAJ |
| description | Mesenchymal stem cells (MSCs) have been known to mankind since the mid-20th century. The comprehensive study revealed their high biologically active potential. Capacity of forming several types of body tissues was demonstrated. The stem cells, like any other cells, exert their effect on surrounding cells and tissues by secreting extracellular vesicles. The extracellular vesicles of the stem cells possess biological activity of parent cells. Taking into account the regenerative potential of the mesenchymal stem cells, they are currently used in medicine, and also in veterinary medicine for treatment of various injuries of the companion animals. Effect of the mesenchymal stem cells on boar and rat sperm cells during 12-hour storage was studied. The study results demonstrated that during 12 hours of coincubation, the porcine MSCs contributed to the survival of the boar sperm cells and maintenance of their motility at 60–80% (depending on the solvent) as compared to the controls. Such a significant effect was not however observed during coincubation of the rat sperm cells with rat MSCs. But it should be noted that before the3rdhour of coincubation, the experimental sperm motility was higher than that of the control. By hour5 of the observation, this difference was leveled. The rat and boar sperm cells are likely to have different physiological characteristics, which were reflected in the results obtained. Therefore, possibility of using the MSCs for the storage and cryopreservation of the semen of some animals was demonstrated, but this requires further research. |
| first_indexed | 2024-04-24T13:58:55Z |
| format | Article |
| id | doaj.art-5ead131d3fe341f698173f64e5c728f0 |
| institution | Directory Open Access Journal |
| issn | 2304-196X 2658-6959 |
| language | English |
| last_indexed | 2025-02-16T03:57:24Z |
| publishDate | 2023-12-01 |
| publisher | Da Vinci Media |
| record_format | Article |
| series | Ветеринария сегодня |
| spelling | doaj.art-5ead131d3fe341f698173f64e5c728f02025-02-06T09:52:10ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592023-12-0112435436210.29326/2304-196X-2023-12-4-354-362643Effect of mesenchymal stem cells on animal semen during storageE. Yu. Zakirova0A. G. Malanyeva1A. M. Aimaletdinov2Institute of Fundamental Medicine and Biology Kazan (Volga region) Federal University (IFMB KFU)Institute of Fundamental Medicine and Biology Kazan (Volga region) Federal University (IFMB KFU)Institute of Fundamental Medicine and Biology Kazan (Volga region) Federal University (IFMB KFU)Mesenchymal stem cells (MSCs) have been known to mankind since the mid-20th century. The comprehensive study revealed their high biologically active potential. Capacity of forming several types of body tissues was demonstrated. The stem cells, like any other cells, exert their effect on surrounding cells and tissues by secreting extracellular vesicles. The extracellular vesicles of the stem cells possess biological activity of parent cells. Taking into account the regenerative potential of the mesenchymal stem cells, they are currently used in medicine, and also in veterinary medicine for treatment of various injuries of the companion animals. Effect of the mesenchymal stem cells on boar and rat sperm cells during 12-hour storage was studied. The study results demonstrated that during 12 hours of coincubation, the porcine MSCs contributed to the survival of the boar sperm cells and maintenance of their motility at 60–80% (depending on the solvent) as compared to the controls. Such a significant effect was not however observed during coincubation of the rat sperm cells with rat MSCs. But it should be noted that before the3rdhour of coincubation, the experimental sperm motility was higher than that of the control. By hour5 of the observation, this difference was leveled. The rat and boar sperm cells are likely to have different physiological characteristics, which were reflected in the results obtained. Therefore, possibility of using the MSCs for the storage and cryopreservation of the semen of some animals was demonstrated, but this requires further research.https://veterinary.arriah.ru/jour/article/view/772mesenchymal stem cells (mscs)pigboarratsperm cells |
| spellingShingle | E. Yu. Zakirova A. G. Malanyeva A. M. Aimaletdinov Effect of mesenchymal stem cells on animal semen during storage Ветеринария сегодня mesenchymal stem cells (mscs) pig boar rat sperm cells |
| title | Effect of mesenchymal stem cells on animal semen during storage |
| title_full | Effect of mesenchymal stem cells on animal semen during storage |
| title_fullStr | Effect of mesenchymal stem cells on animal semen during storage |
| title_full_unstemmed | Effect of mesenchymal stem cells on animal semen during storage |
| title_short | Effect of mesenchymal stem cells on animal semen during storage |
| title_sort | effect of mesenchymal stem cells on animal semen during storage |
| topic | mesenchymal stem cells (mscs) pig boar rat sperm cells |
| url | https://veterinary.arriah.ru/jour/article/view/772 |
| work_keys_str_mv | AT eyuzakirova effectofmesenchymalstemcellsonanimalsemenduringstorage AT agmalanyeva effectofmesenchymalstemcellsonanimalsemenduringstorage AT amaimaletdinov effectofmesenchymalstemcellsonanimalsemenduringstorage |