In silico design of quadruplex aptamers against the spike protein of SARS-CoV-2

In silico design of quadruplex aptamers against the spike protein of SARS-CoV-2

Nucleic acid aptamers are short sequences of nucleic acid ligands that bind to a specific target molecule. Aptamers are experimentally nominated using the well-designed SELEX (systematic evolution of ligands by exponential enrichment) method. Here, we designed a new method for diagnosis and blocking...

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Bibliographic Details
Main Authors: Mandana Behbahani, Hassan Mohabatkar, Barumand Hosseini
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Informatics in Medicine Unlocked
Subjects:
In silico
DNA Aptamer
SARS-CoV-2
Non-SELEX approach
Online Access:http://www.sciencedirect.com/science/article/pii/S235291482100232X

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