Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?

Treatment of brucellosis, a disease which continues to be an important health problem in our country still presents problems for clinicians. The eff›icacies of doxycycline and streptomycin and doxycycline and rifampicin combination are very near. However doxycycline and rifampicin treatment is assoc...

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Main Authors: Dilek İNCE, Murat DİLMENER
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 1997-03-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Subjects:
Online Access:http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-1-012-015.pdf
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author Dilek İNCE
Murat DİLMENER
author_facet Dilek İNCE
Murat DİLMENER
author_sort Dilek İNCE
collection DOAJ
description Treatment of brucellosis, a disease which continues to be an important health problem in our country still presents problems for clinicians. The eff›icacies of doxycycline and streptomycin and doxycycline and rifampicin combination are very near. However doxycycline and rifampicin treatment is associated with a higher relapse rate as well as a higher risk of hepatotoxicity. For the treatment of neurobrucellosis, osteoarticular brucellosis and Brucella abscesses, a three drug regimen consisting of doxycycline, streptomisin and rifampicin or cotrimoxazole should be used. In Brucella endocarditis, combined antimicrobial and surgical valve replacement is indicated.
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spelling doaj.art-5eadeb97ac4e4919bb0e056bfe4765922023-02-15T16:07:43ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X1997-03-01211215Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?Dilek İNCE0Murat DİLMENER1İstanbul Üniversitesi, İstanbul Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim Dalı, İSTANBULİstanbul Üniversitesi, İstanbul Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim Dalı, İSTANBULTreatment of brucellosis, a disease which continues to be an important health problem in our country still presents problems for clinicians. The eff›icacies of doxycycline and streptomycin and doxycycline and rifampicin combination are very near. However doxycycline and rifampicin treatment is associated with a higher relapse rate as well as a higher risk of hepatotoxicity. For the treatment of neurobrucellosis, osteoarticular brucellosis and Brucella abscesses, a three drug regimen consisting of doxycycline, streptomisin and rifampicin or cotrimoxazole should be used. In Brucella endocarditis, combined antimicrobial and surgical valve replacement is indicated.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-1-012-015.pdfBrucellosisTreatmentRelapse
spellingShingle Dilek İNCE
Murat DİLMENER
Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Brucellosis
Treatment
Relapse
title Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?
title_full Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?
title_fullStr Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?
title_full_unstemmed Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?
title_short Treatment of brucellosis: Which antibiotic regimen should be preferred in our country?
title_sort treatment of brucellosis which antibiotic regimen should be preferred in our country
topic Brucellosis
Treatment
Relapse
url http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=1997-2-1-012-015.pdf
work_keys_str_mv AT dilekince treatmentofbrucellosiswhichantibioticregimenshouldbepreferredinourcountry
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