Impact of Hyper- and Hypo-Uricemia on Kidney Function

Impact of Hyper- and Hypo-Uricemia on Kidney Function

Uric acid (UA) forms monosodium urate (MSU) crystals to exert proinflammatory actions, thus causing gout arthritis, urolithiasis, kidney disease, and cardiovascular disease. UA is also one of the most potent antioxidants that suppresses oxidative stress. Hyper andhypouricemia are caused by genetic m...

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Bibliographic Details
Main Authors: Junichiro Miake, Ichiro Hisatome, Katsuyuki Tomita, Tadahiro Isoyama, Shinobu Sugihara, Masanari Kuwabara, Kazuhide Ogino, Haruaki Ninomiya
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
hyperuricemia
hypouricemia
urolithiasis
tubular disease
kidney disease
U-shaped association
Online Access:https://www.mdpi.com/2227-9059/11/5/1258

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