Establishment of a multi-parameter prediction model for the functional cure of HBeAg-negative chronic hepatitis B patients treated with pegylated interferonα and decision process based on response-guided therapy strategy

Establishment of a multi-parameter prediction model for the functional cure of HBeAg-negative chronic hepatitis B patients treated with pegylated interferonα and decision process based on response-guided therapy strategy

Abstract Background & aims This study aimed to establish multivariate prediction models according to a response-guided therapy (RGT) based strategy at baseline and week 12 and 24 of follow-up to predict the functional cure for HBeAg-negative patients with chronic hepatitis B (CHB) treated with p...

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Bibliographic Details
Main Authors: Qianqian Tang, Jun Ye, Yafei Zhang, Peixin Zhang, Guomei Xia, Jie Zhu, Shaofeng Wei, Xu Li, Zhenhua Zhang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Infectious Diseases
Subjects:
Chronic hepatitis B
HBeAg-negative
Hepatitis B surface antigen
Score model
PEG-IFNα
RGT
Online Access:https://doi.org/10.1186/s12879-023-08443-1

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