Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish
Additional roles for A-to-I editing of RNA continue to be uncovered. Niescierowicz et al. report prevalent A-to-I editing in the zebrafish transcriptome, and the distinct maternal and zygotic functions of the editing enzyme Adar in embryonic patterning and in the regulation of innate immune response...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-33260-6 |
| _version_ | 1811265194805952512 |
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| author | Katarzyna Niescierowicz Leszek Pryszcz Cristina Navarrete Eugeniusz Tralle Agata Sulej Karim Abu Nahia Marta Elżbieta Kasprzyk Katarzyna Misztal Abhishek Pateria Adrianna Pakuła Matthias Bochtler Cecilia Winata |
| author_facet | Katarzyna Niescierowicz Leszek Pryszcz Cristina Navarrete Eugeniusz Tralle Agata Sulej Karim Abu Nahia Marta Elżbieta Kasprzyk Katarzyna Misztal Abhishek Pateria Adrianna Pakuła Matthias Bochtler Cecilia Winata |
| author_sort | Katarzyna Niescierowicz |
| collection | DOAJ |
| description | Additional roles for A-to-I editing of RNA continue to be uncovered. Niescierowicz et al. report prevalent A-to-I editing in the zebrafish transcriptome, and the distinct maternal and zygotic functions of the editing enzyme Adar in embryonic patterning and in the regulation of innate immune response, respectively. |
| first_indexed | 2024-04-12T20:18:03Z |
| format | Article |
| id | doaj.art-5ebee68a9d1049d8aa8186465707f125 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T20:18:03Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-5ebee68a9d1049d8aa8186465707f1252022-12-22T03:18:03ZengNature PortfolioNature Communications2041-17232022-09-0113111410.1038/s41467-022-33260-6Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafishKatarzyna Niescierowicz0Leszek Pryszcz1Cristina Navarrete2Eugeniusz Tralle3Agata Sulej4Karim Abu Nahia5Marta Elżbieta Kasprzyk6Katarzyna Misztal7Abhishek Pateria8Adrianna Pakuła9Matthias Bochtler10Cecilia Winata11International Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawInternational Institute of Molecular and Cell Biology in WarsawAdditional roles for A-to-I editing of RNA continue to be uncovered. Niescierowicz et al. report prevalent A-to-I editing in the zebrafish transcriptome, and the distinct maternal and zygotic functions of the editing enzyme Adar in embryonic patterning and in the regulation of innate immune response, respectively.https://doi.org/10.1038/s41467-022-33260-6 |
| spellingShingle | Katarzyna Niescierowicz Leszek Pryszcz Cristina Navarrete Eugeniusz Tralle Agata Sulej Karim Abu Nahia Marta Elżbieta Kasprzyk Katarzyna Misztal Abhishek Pateria Adrianna Pakuła Matthias Bochtler Cecilia Winata Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish Nature Communications |
| title | Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish |
| title_full | Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish |
| title_fullStr | Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish |
| title_full_unstemmed | Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish |
| title_short | Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish |
| title_sort | adar mediated a to i editing is required for embryonic patterning and innate immune response regulation in zebrafish |
| url | https://doi.org/10.1038/s41467-022-33260-6 |
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