Immune response treated with bone marrow mesenchymal stromal cells after stroke
Stroke is a leading cause of death and long-term disability worldwide. Tissue plasminogen activator (tPA) is an effective treatment for ischemic stroke. However, only a small part of patients could benefit from it. Therefore, finding a new treatment is necessary. Bone marrow mesenchymal stromal cell...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.991379/full |
| _version_ | 1798035849245360128 |
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| author | Zili Wang Zili Wang Xudong Wang Xudong Wang Yidong Liao Yidong Liao Guangtang Chen Guangtang Chen Kaya Xu Kaya Xu |
| author_facet | Zili Wang Zili Wang Xudong Wang Xudong Wang Yidong Liao Yidong Liao Guangtang Chen Guangtang Chen Kaya Xu Kaya Xu |
| author_sort | Zili Wang |
| collection | DOAJ |
| description | Stroke is a leading cause of death and long-term disability worldwide. Tissue plasminogen activator (tPA) is an effective treatment for ischemic stroke. However, only a small part of patients could benefit from it. Therefore, finding a new treatment is necessary. Bone marrow mesenchymal stromal cells (BMSCs) provide a novel strategy for stroke patients. Now, many patients take stem cells to treat stroke. However, the researches of the precise inflammatory mechanism of cell replacement treatment are still rare. In this review, we summarize the immune response of BMSCs treated to stroke and may provide a new perspective for stem cell therapy. |
| first_indexed | 2024-04-11T21:02:58Z |
| format | Article |
| id | doaj.art-5ebf82e7c1ce430a9fd4c0bcada1aea4 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-11T21:02:58Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-5ebf82e7c1ce430a9fd4c0bcada1aea42022-12-22T04:03:25ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-09-011310.3389/fneur.2022.991379991379Immune response treated with bone marrow mesenchymal stromal cells after strokeZili Wang0Zili Wang1Xudong Wang2Xudong Wang3Yidong Liao4Yidong Liao5Guangtang Chen6Guangtang Chen7Kaya Xu8Kaya Xu9Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, ChinaDepartment of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaSchool of Clinical Medicine, Guizhou Medical University, Guiyang, ChinaStroke is a leading cause of death and long-term disability worldwide. Tissue plasminogen activator (tPA) is an effective treatment for ischemic stroke. However, only a small part of patients could benefit from it. Therefore, finding a new treatment is necessary. Bone marrow mesenchymal stromal cells (BMSCs) provide a novel strategy for stroke patients. Now, many patients take stem cells to treat stroke. However, the researches of the precise inflammatory mechanism of cell replacement treatment are still rare. In this review, we summarize the immune response of BMSCs treated to stroke and may provide a new perspective for stem cell therapy.https://www.frontiersin.org/articles/10.3389/fneur.2022.991379/fullstrokebone marrow mesenchymal stromal cellstem cell therapyinflammationneuroprotection |
| spellingShingle | Zili Wang Zili Wang Xudong Wang Xudong Wang Yidong Liao Yidong Liao Guangtang Chen Guangtang Chen Kaya Xu Kaya Xu Immune response treated with bone marrow mesenchymal stromal cells after stroke Frontiers in Neurology stroke bone marrow mesenchymal stromal cell stem cell therapy inflammation neuroprotection |
| title | Immune response treated with bone marrow mesenchymal stromal cells after stroke |
| title_full | Immune response treated with bone marrow mesenchymal stromal cells after stroke |
| title_fullStr | Immune response treated with bone marrow mesenchymal stromal cells after stroke |
| title_full_unstemmed | Immune response treated with bone marrow mesenchymal stromal cells after stroke |
| title_short | Immune response treated with bone marrow mesenchymal stromal cells after stroke |
| title_sort | immune response treated with bone marrow mesenchymal stromal cells after stroke |
| topic | stroke bone marrow mesenchymal stromal cell stem cell therapy inflammation neuroprotection |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.991379/full |
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