Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility
Foxtail millet (Setaria italica) has a long history of treating gastrointestinal ailments in China; however, little is known about the functional mechanism driving its therapeutic effects. The primary edible form of millet is porridge. This study investigates the effects of millet porridge on diphen...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.965687/full |
| _version_ | 1811340731110916096 |
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| author | Ying Chen Ying Chen Rong Zhang Jialiang Xu Jialiang Xu Qing Ren Qing Ren |
| author_facet | Ying Chen Ying Chen Rong Zhang Jialiang Xu Jialiang Xu Qing Ren Qing Ren |
| author_sort | Ying Chen |
| collection | DOAJ |
| description | Foxtail millet (Setaria italica) has a long history of treating gastrointestinal ailments in China; however, little is known about the functional mechanism driving its therapeutic effects. The primary edible form of millet is porridge. This study investigates the effects of millet porridge on diphenoxylate-induced constipation and intestinal microflora in mice. Fifty mice were randomly divided into five groups: normal control group, constipation model group, and low-dose, medium-dose, and high-dose millet porridge groups. After 14 days of millet porridge gavage, constipation was induced and measured. The results showed that millet porridge prevented constipation by increasing the water content of feces, shortened the time of the first melena defecation, promoted gastric emptying, and improved the rate of gastrointestinal propulsion. Millet porridge also dose-dependently increased levels of Bifidobacterium and Lactobacillus and decreased levels of Escherichia coli, Enterococcus, and Bacteroides in the intestine. These results show that millet porridge could accelerate intestinal motility and change the proportions of intestinal flora and that it has a potent prebiotic effect. |
| first_indexed | 2024-04-13T18:46:13Z |
| format | Article |
| id | doaj.art-5ec29eec2810457f9917f70cd253cf96 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-13T18:46:13Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-5ec29eec2810457f9917f70cd253cf962022-12-22T02:34:34ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-08-01910.3389/fnut.2022.965687965687Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motilityYing Chen0Ying Chen1Rong Zhang2Jialiang Xu3Jialiang Xu4Qing Ren5Qing Ren6School of Light Industry, Beijing Technology and Business University, Beijing, ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing, ChinaXinjiang Second Medical College, Karamay, ChinaSchool of Light Industry, Beijing Technology and Business University, Beijing, ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing, ChinaSchool of Light Industry, Beijing Technology and Business University, Beijing, ChinaBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing, ChinaFoxtail millet (Setaria italica) has a long history of treating gastrointestinal ailments in China; however, little is known about the functional mechanism driving its therapeutic effects. The primary edible form of millet is porridge. This study investigates the effects of millet porridge on diphenoxylate-induced constipation and intestinal microflora in mice. Fifty mice were randomly divided into five groups: normal control group, constipation model group, and low-dose, medium-dose, and high-dose millet porridge groups. After 14 days of millet porridge gavage, constipation was induced and measured. The results showed that millet porridge prevented constipation by increasing the water content of feces, shortened the time of the first melena defecation, promoted gastric emptying, and improved the rate of gastrointestinal propulsion. Millet porridge also dose-dependently increased levels of Bifidobacterium and Lactobacillus and decreased levels of Escherichia coli, Enterococcus, and Bacteroides in the intestine. These results show that millet porridge could accelerate intestinal motility and change the proportions of intestinal flora and that it has a potent prebiotic effect.https://www.frontiersin.org/articles/10.3389/fnut.2022.965687/fullfoxtail milletintestinal microfloraconstipationprebioticgastrointestinal motility |
| spellingShingle | Ying Chen Ying Chen Rong Zhang Jialiang Xu Jialiang Xu Qing Ren Qing Ren Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility Frontiers in Nutrition foxtail millet intestinal microflora constipation prebiotic gastrointestinal motility |
| title | Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility |
| title_full | Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility |
| title_fullStr | Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility |
| title_full_unstemmed | Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility |
| title_short | Alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility |
| title_sort | alteration of intestinal microflora by the intake of millet porridge improves gastrointestinal motility |
| topic | foxtail millet intestinal microflora constipation prebiotic gastrointestinal motility |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.965687/full |
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