Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution

Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution

Influenza A virus (IAV) is an important human respiratory pathogen that causes significant seasonal epidemics and potential devastating pandemics. As part of its life cycle, IAV encodes the multifunctional protein NS1, that, among many roles, prevents immune detection and limits interferon (IFN) pro...

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Bibliographic Details
Main Authors: Qing Yang, Anna E. Elz, Maryline Panis, Ting Liu, Benjamin E. Nilsson-Payant, Daniel Blanco-Melo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Microbiology
Subjects:
influenza
NS1
interferon
immune antagonism
innate immune response
unfolded protein response
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1267078/full

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