Inhibition enhances spatially-specific calcium encoding of synaptic input patterns in a biologically constrained model
Synaptic plasticity, which underlies learning and memory, depends on calcium elevation in neurons, but the precise relationship between calcium and spatiotemporal patterns of synaptic inputs is unclear. Here, we develop a biologically realistic computational model of striatal spiny projection neuron...
Main Authors: | Daniel B Dorman, Joanna Jędrzejewska-Szmek, Kim T Blackwell |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/38588 |
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