Premature commitment to uncertain decisions during human NMDA receptor hypofunction
In uncertain conditions, people make accurate decisions by considering multiple pieces of information. Here, the authors show that pharmacological n-methyl-d-aspartate (NMDA) receptor hypofunction is associated with elevated uncertainty and premature decisions based on unreliable evidence.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-27876-3 |
| _version_ | 1818954042190069760 |
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| author | Alexandre Salvador Luc H. Arnal Fabien Vinckier Philippe Domenech Raphaël Gaillard Valentin Wyart |
| author_facet | Alexandre Salvador Luc H. Arnal Fabien Vinckier Philippe Domenech Raphaël Gaillard Valentin Wyart |
| author_sort | Alexandre Salvador |
| collection | DOAJ |
| description | In uncertain conditions, people make accurate decisions by considering multiple pieces of information. Here, the authors show that pharmacological n-methyl-d-aspartate (NMDA) receptor hypofunction is associated with elevated uncertainty and premature decisions based on unreliable evidence. |
| first_indexed | 2024-12-20T10:15:52Z |
| format | Article |
| id | doaj.art-5ec88241d00249469b086de47c85dcf2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T10:15:52Z |
| publishDate | 2022-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-5ec88241d00249469b086de47c85dcf22022-12-21T19:44:04ZengNature PortfolioNature Communications2041-17232022-01-0113111510.1038/s41467-021-27876-3Premature commitment to uncertain decisions during human NMDA receptor hypofunctionAlexandre Salvador0Luc H. Arnal1Fabien Vinckier2Philippe Domenech3Raphaël Gaillard4Valentin Wyart5Laboratoire de Neurosciences Cognitives et Computationnelles, Institut National de la Santé et de la Recherche MédicaleInstitut de l’Audition, Inserm unit 1120, Institut PasteurUniversité de ParisÉquipe Neurophysiologie des Comportements Répétitifs, Institut du Cerveau, Sorbonne UniversitéUniversité de ParisLaboratoire de Neurosciences Cognitives et Computationnelles, Institut National de la Santé et de la Recherche MédicaleIn uncertain conditions, people make accurate decisions by considering multiple pieces of information. Here, the authors show that pharmacological n-methyl-d-aspartate (NMDA) receptor hypofunction is associated with elevated uncertainty and premature decisions based on unreliable evidence.https://doi.org/10.1038/s41467-021-27876-3 |
| spellingShingle | Alexandre Salvador Luc H. Arnal Fabien Vinckier Philippe Domenech Raphaël Gaillard Valentin Wyart Premature commitment to uncertain decisions during human NMDA receptor hypofunction Nature Communications |
| title | Premature commitment to uncertain decisions during human NMDA receptor hypofunction |
| title_full | Premature commitment to uncertain decisions during human NMDA receptor hypofunction |
| title_fullStr | Premature commitment to uncertain decisions during human NMDA receptor hypofunction |
| title_full_unstemmed | Premature commitment to uncertain decisions during human NMDA receptor hypofunction |
| title_short | Premature commitment to uncertain decisions during human NMDA receptor hypofunction |
| title_sort | premature commitment to uncertain decisions during human nmda receptor hypofunction |
| url | https://doi.org/10.1038/s41467-021-27876-3 |
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