Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis

Abstract Background Hypertension is a major public health problem, resulting in 10 million deaths annually. Undiagnosed hypertension affects more people than ever before. It is more likely to be linked to severe hypertension, which can lead to stroke, cardiovascular disease, and ischemic heart disea...

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Main Authors: Gizachew Ambaw Kassie, Afework Alemu, Amanuel Yosef Gebrekidan, Getachew Asmare Adella, Kirubel Eshetu, Abiyot Wolie Asres, Yordanos Sisay Asgedom
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-023-03300-0
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author Gizachew Ambaw Kassie
Afework Alemu
Amanuel Yosef Gebrekidan
Getachew Asmare Adella
Kirubel Eshetu
Abiyot Wolie Asres
Yordanos Sisay Asgedom
author_facet Gizachew Ambaw Kassie
Afework Alemu
Amanuel Yosef Gebrekidan
Getachew Asmare Adella
Kirubel Eshetu
Abiyot Wolie Asres
Yordanos Sisay Asgedom
author_sort Gizachew Ambaw Kassie
collection DOAJ
description Abstract Background Hypertension is a major public health problem, resulting in 10 million deaths annually. Undiagnosed hypertension affects more people than ever before. It is more likely to be linked to severe hypertension, which can lead to stroke, cardiovascular disease, and ischemic heart disease. Thus, this systematic review and meta-analysis aimed to synthesize the prevalence of undiagnosed hypertension and its associated factors in Ethiopia. Methods Databases, such as Medline/PubMed, Google Scholar, Science Direct, AJOL, and the Cochrane Library, were systematically searched to find potential studies published until December 2022. A Microsoft Excel spreadsheet was used to enter the extracted data. The pooled prevalence of undiagnosed hypertension and its associated factors was estimated using a random effect model. I2 statistics and the Cochrane Q-test were used to assess statistical heterogeneity across the studies. Begg’s and Egger’s tests were performed to identify possible publication bias. Results A total of ten articles with 5,782 study participants were included in this meta-analysis. In the random effects model, the pooled prevalence of undiagnosed hypertension was 18.26% (95% CI = 14.94–21.58). Being older (OR = 3.8, 95% CI = 2.56, 5.66), having a body mass index > 25 kg/m2 (OR = 2.71, 95% CI = 2.1, 3.53), having a family history of hypertension (OR = 2.22, 95% CI = 1.47, 3.36), and having DM comorbidity (OR = 2.44, 95% CI = 1.38, 4.32) were significantly associated with undiagnosed hypertension. Conclusion In this meta-analysis, the pooled prevalence of undiagnosed hypertension was found to be high in Ethiopia. Being older, having a BMI > 25 kg/m2, having a family history of hypertension, and having DM comorbidity were found to be risk factors for undiagnosed hypertension.
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spelling doaj.art-5ecfb5ce15b6496faa0d43c8be3ab0c32023-05-28T11:07:53ZengBMCBMC Cardiovascular Disorders1471-22612023-05-0123111510.1186/s12872-023-03300-0Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysisGizachew Ambaw Kassie0Afework Alemu1Amanuel Yosef Gebrekidan2Getachew Asmare Adella3Kirubel Eshetu4Abiyot Wolie Asres5Yordanos Sisay Asgedom6School of Public Health, College of Health Science and Medicine, Wolaita Sodo UniversitySchool of Medicine, College of Health Science and Medicine, Wolaita Sodo UniversitySchool of Public Health, College of Health Science and Medicine, Wolaita Sodo UniversitySchool of Public Health, College of Health Science and Medicine, Wolaita Sodo UniversitySchool of Nursing, College of Health Science and Medicine, Wolaita Sodo UniversitySchool of Public Health, College of Health Science and Medicine, Wolaita Sodo UniversitySchool of Public Health, College of Health Science and Medicine, Wolaita Sodo UniversityAbstract Background Hypertension is a major public health problem, resulting in 10 million deaths annually. Undiagnosed hypertension affects more people than ever before. It is more likely to be linked to severe hypertension, which can lead to stroke, cardiovascular disease, and ischemic heart disease. Thus, this systematic review and meta-analysis aimed to synthesize the prevalence of undiagnosed hypertension and its associated factors in Ethiopia. Methods Databases, such as Medline/PubMed, Google Scholar, Science Direct, AJOL, and the Cochrane Library, were systematically searched to find potential studies published until December 2022. A Microsoft Excel spreadsheet was used to enter the extracted data. The pooled prevalence of undiagnosed hypertension and its associated factors was estimated using a random effect model. I2 statistics and the Cochrane Q-test were used to assess statistical heterogeneity across the studies. Begg’s and Egger’s tests were performed to identify possible publication bias. Results A total of ten articles with 5,782 study participants were included in this meta-analysis. In the random effects model, the pooled prevalence of undiagnosed hypertension was 18.26% (95% CI = 14.94–21.58). Being older (OR = 3.8, 95% CI = 2.56, 5.66), having a body mass index > 25 kg/m2 (OR = 2.71, 95% CI = 2.1, 3.53), having a family history of hypertension (OR = 2.22, 95% CI = 1.47, 3.36), and having DM comorbidity (OR = 2.44, 95% CI = 1.38, 4.32) were significantly associated with undiagnosed hypertension. Conclusion In this meta-analysis, the pooled prevalence of undiagnosed hypertension was found to be high in Ethiopia. Being older, having a BMI > 25 kg/m2, having a family history of hypertension, and having DM comorbidity were found to be risk factors for undiagnosed hypertension.https://doi.org/10.1186/s12872-023-03300-0Undiagnosed hypertensionSystematic reviewMeta-analysisEthiopia
spellingShingle Gizachew Ambaw Kassie
Afework Alemu
Amanuel Yosef Gebrekidan
Getachew Asmare Adella
Kirubel Eshetu
Abiyot Wolie Asres
Yordanos Sisay Asgedom
Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis
BMC Cardiovascular Disorders
Undiagnosed hypertension
Systematic review
Meta-analysis
Ethiopia
title Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis
title_full Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis
title_fullStr Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis
title_full_unstemmed Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis
title_short Undiagnosed hypertension and associated factors among adults in ethiopia: a systematic review and meta-analysis
title_sort undiagnosed hypertension and associated factors among adults in ethiopia a systematic review and meta analysis
topic Undiagnosed hypertension
Systematic review
Meta-analysis
Ethiopia
url https://doi.org/10.1186/s12872-023-03300-0
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