Data-driven causal model discovery and personalized prediction in Alzheimer's disease

Abstract With the explosive growth of biomarker data in Alzheimer’s disease (AD) clinical trials, numerous mathematical models have been developed to characterize disease-relevant biomarker trajectories over time. While some of these models are purely empiric, others are causal, built upon various h...

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Bibliographic Details
Main Authors: Haoyang Zheng, Jeffrey R. Petrella, P. Murali Doraiswamy, Guang Lin, Wenrui Hao, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-022-00632-7