Oxidative Stress, Inflammation, and Activators of Mitochondrial Biogenesis: Tempol Targets in the Diaphragm Muscle of Exercise Trained-mdx Mice

Oxidative Stress, Inflammation, and Activators of Mitochondrial Biogenesis: Tempol Targets in the Diaphragm Muscle of Exercise Trained-mdx Mice

The mdx mouse phenotype aggravated by chronic exercise on a treadmill makes this murine model more reliable for the study of muscular dystrophy. Thus, to better assess the Tempol effect on dystrophic pathways, the analyses in this study were performed in the blood samples and diaphragm muscle from t...

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Bibliographic Details
Main Authors: Heloina Nathalliê Mariano da Silva, Caroline Covatti, Guilherme Luiz da Rocha, Daniela Sayuri Mizobuti, Rafael Dias Mâncio, Túlio de Almeida Hermes, Larissa Akemi Kido, Valéria Helena Alves Cagnon, Elaine Cristina Leite Pereira, Elaine Minatel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Physiology
Subjects:
tempol
dystrophic muscles
exercise
oxidative stress
inflammatory process
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.649793/full

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