Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

<p>Abstract</p> <p>Background</p> <p>Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of c...

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Bibliographic Details
Main Authors: Sun Ramon C, Board Philip G, Blackburn Anneke C
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Molecular Cancer
Subjects:
Dichloroacetate
breast cancer
electron transport chain
mitochondria
arsenic trioxide
Online Access:http://www.molecular-cancer.com/content/10/1/142

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