EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS

The effect of the rocket juice Eruca sativa (A cruciferous plant ) and its counter effect on chromosomal aberrations induced by Cyclophosphamide (Cp) drug was studied in white mice bone marrow cells .The effect of different combinations of plant juice and mutagen was studied to find out the patterns...

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Main Author: Ilham A. Khalaf
Format: Article
Language:Arabic
Published: College of Agriculture 2009-06-01
Series:Mesopotamia Journal of Agriculture
Online Access:https://magrj.mosuljournals.com/article_27407_9122b47ccd93e3b6ea641773590234df.pdf
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author Ilham A. Khalaf
author_facet Ilham A. Khalaf
author_sort Ilham A. Khalaf
collection DOAJ
description The effect of the rocket juice Eruca sativa (A cruciferous plant ) and its counter effect on chromosomal aberrations induced by Cyclophosphamide (Cp) drug was studied in white mice bone marrow cells .The effect of different combinations of plant juice and mutagen was studied to find out the patterns of protection exert on the aberrations . Results revealed that rocket juice 0.1 , 0.25 , 0.5 / ml animal administrated orally had no effect on induction of chromosomal aberrations , while Cp administrated orally (50 mg / Kg of body weight) , increased the chromosomal aberrations 7 – 11 times of the natural level (Negative control) . Natural repair and activities failed to restore the natural levels as the aberrations still very high .The structural chromosomal aberrations (Chromosome breaks , chromatid breaks , ring chromosomes , and dicentric chromosomes ) induced by Cp were lowered upon using the juice before or after or with the mutagen with significant difference . The prevention (Protection) was proportional to time intervals of treatments , and reached its maximum value (91 % ) when treatment with juice before treatment with mutagen was conducted for 6 days .
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spelling doaj.art-5ed62214ac77408f939ff71ec5ced8602022-12-21T20:31:11ZaraCollege of AgricultureMesopotamia Journal of Agriculture1815-316X2224-97962009-06-0137217518410.33899/magrj.2009.2740727407EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLSIlham A. KhalafThe effect of the rocket juice Eruca sativa (A cruciferous plant ) and its counter effect on chromosomal aberrations induced by Cyclophosphamide (Cp) drug was studied in white mice bone marrow cells .The effect of different combinations of plant juice and mutagen was studied to find out the patterns of protection exert on the aberrations . Results revealed that rocket juice 0.1 , 0.25 , 0.5 / ml animal administrated orally had no effect on induction of chromosomal aberrations , while Cp administrated orally (50 mg / Kg of body weight) , increased the chromosomal aberrations 7 – 11 times of the natural level (Negative control) . Natural repair and activities failed to restore the natural levels as the aberrations still very high .The structural chromosomal aberrations (Chromosome breaks , chromatid breaks , ring chromosomes , and dicentric chromosomes ) induced by Cp were lowered upon using the juice before or after or with the mutagen with significant difference . The prevention (Protection) was proportional to time intervals of treatments , and reached its maximum value (91 % ) when treatment with juice before treatment with mutagen was conducted for 6 days .https://magrj.mosuljournals.com/article_27407_9122b47ccd93e3b6ea641773590234df.pdf
spellingShingle Ilham A. Khalaf
EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS
Mesopotamia Journal of Agriculture
title EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS
title_full EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS
title_fullStr EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS
title_full_unstemmed EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS
title_short EFFECT OF ROCKET LEAVE JUICE (ERUCA SATIVA) JUICE ON CHROMOSOMAL ABERRATIONS OF WHITE MICE BONE MARROW CELLS
title_sort effect of rocket leave juice eruca sativa juice on chromosomal aberrations of white mice bone marrow cells
url https://magrj.mosuljournals.com/article_27407_9122b47ccd93e3b6ea641773590234df.pdf
work_keys_str_mv AT ilhamakhalaf effectofrocketleavejuiceerucasativajuiceonchromosomalaberrationsofwhitemicebonemarrowcells