Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans
The aim of this study was to investigate the effects of thyme endophytes belonging to the Lordegan region on Shigella sonnei and Candida albicans. Thyme components were immersed in 70% ethanol (2 minutes), 3.5% sodium hypochlorite (5 minutes), and 75% ethanol (30 seconds), respectively, and lastly...
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| Format: | Article |
| Language: | fas |
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Islamic Azad University, Tabriz Branch
2023-02-01
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| Series: | Bihdāsht-i Mavādd-i Ghaz̠āyī |
| Subjects: | |
| Online Access: | https://jfh.tabriz.iau.ir/article_702394_0f1abeae6a934d658808e8f0331afafd.pdf |
| _version_ | 1797664803157704704 |
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| author | somayeh shahrokh shahraki mohammad khodadadi Azam mokhtari |
| author_facet | somayeh shahrokh shahraki mohammad khodadadi Azam mokhtari |
| author_sort | somayeh shahrokh shahraki |
| collection | DOAJ |
| description | The aim of this study was to investigate the effects of thyme endophytes belonging to the Lordegan region on Shigella sonnei and Candida albicans. Thyme components were immersed in 70% ethanol (2 minutes), 3.5% sodium hypochlorite (5 minutes), and 75% ethanol (30 seconds), respectively, and lastly washed with sterile distilled water. Subsequently, they were cultured on YEA and PA medium, and the endophytes were isolated. A total of 8 bacterial endophytes were taken from different parts of the Lordegan thyme plant (stem, leaves, and roots) and examined. The endophytes isolated from thyme were bacilli, coccobacilli, and cocci. Antimicrobial and inhibitory properties of endophytes isolated from Lordegan thyme were studied in two methods: structural factors and secretory metabolites of endophytes. The results of this study showed the beneficial effects of thyme endophytes on Shigella sonnei and Candida albicans. Bacterial endophytes isolated from thyme (roots stems and leaves) showed stronger inhibitory effects than the study of secretory metabolites against S. sonnei and C. albicans. In general, thyme could be a good alternative to chemical drugs in the treatment of Candida infections, especially cutaneous mucosal candidiasis, and shigellosis, and can be used in therapeutic cases, food, health, and pharmaceutical industries. |
| first_indexed | 2024-03-11T19:34:37Z |
| format | Article |
| id | doaj.art-5ed65d1522944039a769bf8f3d2f2964 |
| institution | Directory Open Access Journal |
| issn | 2228-7647 2476-6968 |
| language | fas |
| last_indexed | 2024-03-11T19:34:37Z |
| publishDate | 2023-02-01 |
| publisher | Islamic Azad University, Tabriz Branch |
| record_format | Article |
| series | Bihdāsht-i Mavādd-i Ghaz̠āyī |
| spelling | doaj.art-5ed65d1522944039a769bf8f3d2f29642023-10-06T13:12:57ZfasIslamic Azad University, Tabriz BranchBihdāsht-i Mavādd-i Ghaz̠āyī2228-76472476-69682023-02-01124 (48) زمستان172910.30495/jfh.2023.1978116.1389702394Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicanssomayeh shahrokh shahraki0mohammad khodadadi1Azam mokhtari22. Research Institute of Zoonotic Diseases, Shahrekord University, Shahrekord, IranDepartment of Pathobiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran2. Research Institute of Zoonotic Diseases, Shahrekord University, Shahrekord, IranThe aim of this study was to investigate the effects of thyme endophytes belonging to the Lordegan region on Shigella sonnei and Candida albicans. Thyme components were immersed in 70% ethanol (2 minutes), 3.5% sodium hypochlorite (5 minutes), and 75% ethanol (30 seconds), respectively, and lastly washed with sterile distilled water. Subsequently, they were cultured on YEA and PA medium, and the endophytes were isolated. A total of 8 bacterial endophytes were taken from different parts of the Lordegan thyme plant (stem, leaves, and roots) and examined. The endophytes isolated from thyme were bacilli, coccobacilli, and cocci. Antimicrobial and inhibitory properties of endophytes isolated from Lordegan thyme were studied in two methods: structural factors and secretory metabolites of endophytes. The results of this study showed the beneficial effects of thyme endophytes on Shigella sonnei and Candida albicans. Bacterial endophytes isolated from thyme (roots stems and leaves) showed stronger inhibitory effects than the study of secretory metabolites against S. sonnei and C. albicans. In general, thyme could be a good alternative to chemical drugs in the treatment of Candida infections, especially cutaneous mucosal candidiasis, and shigellosis, and can be used in therapeutic cases, food, health, and pharmaceutical industries.https://jfh.tabriz.iau.ir/article_702394_0f1abeae6a934d658808e8f0331afafd.pdfendophytelordegan thymeshigella sonneicandida albicans |
| spellingShingle | somayeh shahrokh shahraki mohammad khodadadi Azam mokhtari Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans Bihdāsht-i Mavādd-i Ghaz̠āyī endophyte lordegan thyme shigella sonnei candida albicans |
| title | Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans |
| title_full | Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans |
| title_fullStr | Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans |
| title_full_unstemmed | Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans |
| title_short | Effects of Lordegan Thyme endophytes on Shigella sonnei and Candida albicans |
| title_sort | effects of lordegan thyme endophytes on shigella sonnei and candida albicans |
| topic | endophyte lordegan thyme shigella sonnei candida albicans |
| url | https://jfh.tabriz.iau.ir/article_702394_0f1abeae6a934d658808e8f0331afafd.pdf |
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