Th17/Treg imbalance is associated with reduced indoleamine 2,3 dioxygenase activity in childhood allergic asthma

Th17/Treg imbalance is associated with reduced indoleamine 2,3 dioxygenase activity in childhood allergic asthma

Abstract Background The differentiation of CD4+ lymphocytes Th17/regulatory T cells (Treg) and indoleamine 2,3-dioxygenase (IDO) is associated with the pathogenesis of allergic asthma. Basic research has shown that IDO is likely a “switch” of the transition from Th17 cells to Tregs under certain con...

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Bibliographic Details
Main Authors: Ying Hu, Zhiqiang Chen, Jing Zeng, Shouyan Zheng, Liujuan Sun, Li Zhu, Wei Liao
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Th17/Treg imbalance
IDO
Childhood allergic asthma
Online Access:http://link.springer.com/article/10.1186/s13223-020-00457-7

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