A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19
The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emph...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-11-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/10760296211051764 |
| _version_ | 1818837466414579712 |
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| author | Mark Klein MD Vinh Dao PharmD, BCPS Fatima Khan MD, MPH |
| author_facet | Mark Klein MD Vinh Dao PharmD, BCPS Fatima Khan MD, MPH |
| author_sort | Mark Klein MD |
| collection | DOAJ |
| description | The precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emphasizes the similarities between the physiological effects of platelet activating factor and the clinical complications of severe COVID-19. |
| first_indexed | 2024-12-19T03:22:57Z |
| format | Article |
| id | doaj.art-5edbd1c1c50a4406b493905b9187d87f |
| institution | Directory Open Access Journal |
| issn | 1938-2723 |
| language | English |
| last_indexed | 2024-12-19T03:22:57Z |
| publishDate | 2021-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj.art-5edbd1c1c50a4406b493905b9187d87f2022-12-21T20:37:44ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232021-11-012710.1177/10760296211051764A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19Mark Klein MD0Vinh Dao PharmD, BCPS1Fatima Khan MD, MPH2 University of Minnesota, MN, USA , Minneapolis, MN, 55417, USA University of Minnesota, MN, USAThe precise mechanisms of pathology in severe COVID-19 remains elusive. Current evidence suggests that inflammatory mediators are responsible for the manifestation of clinical symptoms that precedes a fatal response to infection. This review examines the nature of platelet activating factor and emphasizes the similarities between the physiological effects of platelet activating factor and the clinical complications of severe COVID-19.https://doi.org/10.1177/10760296211051764 |
| spellingShingle | Mark Klein MD Vinh Dao PharmD, BCPS Fatima Khan MD, MPH A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 Clinical and Applied Thrombosis/Hemostasis |
| title | A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 |
| title_full | A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 |
| title_fullStr | A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 |
| title_full_unstemmed | A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 |
| title_short | A Review of Platelet-Activating Factor As a Potential Contributor to Morbidity and Mortality Associated with Severe COVID-19 |
| title_sort | review of platelet activating factor as a potential contributor to morbidity and mortality associated with severe covid 19 |
| url | https://doi.org/10.1177/10760296211051764 |
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