CDX2 Enhances HTR-8/SVneo Trophoblast Cell Invasion by Altering the Expression of Matrix Metalloproteinases

CDX2 Enhances HTR-8/SVneo Trophoblast Cell Invasion by Altering the Expression of Matrix Metalloproteinases

Background/Aims: The invasion of trophoblast cells into the maternal uterine decidua is critical for normal placentation, establishment of pregnancy and maintenance of fetal growth in humans. Several growth factors and cytokines have been implicated in trophoblast invasion, but the underlying regula...

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Bibliographic Details
Main Authors: Rui-Zhe Jia, Gui-Chun Ding, Chun-Mei Gu, Tao Huang, Can Rui, Yi-Xiong Wang, Qin Lu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
CDX2
HTR-8/SVneo cell line
Trophoblast invasion
PI3K/Akt
Online Access:http://www.karger.com/Article/FullText/363028

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