Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila

Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila

We use the myotendinous junction of Drosophila flight muscles to explore why many integrin associated proteins (IAPs) are needed and how their function is coordinated. These muscles revealed new functions for IAPs not required for viability: Focal Adhesion Kinase (FAK), RSU1, tensin and vinculin. Ge...

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Bibliographic Details
Main Authors: Hannah J Green, Annabel GM Griffiths, Jari Ylänne, Nicholas H Brown
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
cell-ECM adhesion
myotendinous junction
actin cytoskeleton
integrin
vinculin
filamin
Online Access:https://elifesciences.org/articles/35783

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