Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia

Andersen et al. evaluate lymphocyte dynamics in chronic lymphocytic leukemia (CLL) patients prior to diagnosis. The authors develop a model to predict risk of requiring CLL treatment or death based on pre-diagnostic lymphocyte growth rates.

Bibliographic Details
Main Authors: Michael Asger Andersen, Mia Klinten Grand, Christian Brieghel, Volkert Siersma, Christen Lykkegaard Andersen, Carsten Utoft Niemann
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-022-00117-4
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author Michael Asger Andersen
Mia Klinten Grand
Christian Brieghel
Volkert Siersma
Christen Lykkegaard Andersen
Carsten Utoft Niemann
author_facet Michael Asger Andersen
Mia Klinten Grand
Christian Brieghel
Volkert Siersma
Christen Lykkegaard Andersen
Carsten Utoft Niemann
author_sort Michael Asger Andersen
collection DOAJ
description Andersen et al. evaluate lymphocyte dynamics in chronic lymphocytic leukemia (CLL) patients prior to diagnosis. The authors develop a model to predict risk of requiring CLL treatment or death based on pre-diagnostic lymphocyte growth rates.
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spelling doaj.art-5ee145af7a234908a323efeec13093d82022-12-22T00:38:22ZengNature PortfolioCommunications Medicine2730-664X2022-05-01211810.1038/s43856-022-00117-4Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemiaMichael Asger Andersen0Mia Klinten Grand1Christian Brieghel2Volkert Siersma3Christen Lykkegaard Andersen4Carsten Utoft Niemann5Department of Hematology, Rigshospitalet, Copenhagen University HospitalThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of CopenhagenDepartment of Hematology, Rigshospitalet, Copenhagen University HospitalThe Research Unit for General Practice and Section of General Practice, Department of Public Health, University of CopenhagenDepartment of Hematology, Rigshospitalet, Copenhagen University HospitalDepartment of Hematology, Rigshospitalet, Copenhagen University HospitalAndersen et al. evaluate lymphocyte dynamics in chronic lymphocytic leukemia (CLL) patients prior to diagnosis. The authors develop a model to predict risk of requiring CLL treatment or death based on pre-diagnostic lymphocyte growth rates.https://doi.org/10.1038/s43856-022-00117-4
spellingShingle Michael Asger Andersen
Mia Klinten Grand
Christian Brieghel
Volkert Siersma
Christen Lykkegaard Andersen
Carsten Utoft Niemann
Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
Communications Medicine
title Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
title_full Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
title_fullStr Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
title_full_unstemmed Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
title_short Pre-diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
title_sort pre diagnostic trajectories of lymphocytosis predict time to treatment and death in patients with chronic lymphocytic leukemia
url https://doi.org/10.1038/s43856-022-00117-4
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