Idiopathic nodular glomerulosclerosis and differential diagnosis
ABSTRACT Introduction: Idiopathic nodular glomerulosclerosis (ING) is a condition that has a vasculopathic glomerular histological pattern. Case presentation: The authors present the case of a 44-year-old Hispanic smoker female with hypertension and peripheral arterial disease who presented nephro...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Nefrologia
2020-08-01
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| Series: | Brazilian Journal of Nephrology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400484&tlng=en |
| _version_ | 1819284778530111488 |
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| author | Sergio Raúl Alvizures Solares Héctor Raúl Ibarra-Sifuentes María Guadalupe Ramírez Ramírez Giovanna Yazmin Arteaga Muller Jesús Cruz Valdez |
| author_facet | Sergio Raúl Alvizures Solares Héctor Raúl Ibarra-Sifuentes María Guadalupe Ramírez Ramírez Giovanna Yazmin Arteaga Muller Jesús Cruz Valdez |
| author_sort | Sergio Raúl Alvizures Solares |
| collection | DOAJ |
| description | ABSTRACT Introduction: Idiopathic nodular glomerulosclerosis (ING) is a condition that has a vasculopathic glomerular histological pattern. Case presentation: The authors present the case of a 44-year-old Hispanic smoker female with hypertension and peripheral arterial disease who presented nephrotic syndrome for 2 weeks. The patient was diagnosed with ING by percutaneous renal biopsy results, which showed global nodular mesangial matrix expansion, with linear staining accentuation of glomerular and tubular basement membrane for Immunoglobulin G (IgG) and albumin on immunofluorescence. Conclusions: ING is a rare disease with a poor renal prognosis and wide diagnostic approach; we highlight the importance of analyzing every piece of detail together to reach a definitive diagnosis. |
| first_indexed | 2024-12-24T01:52:47Z |
| format | Article |
| id | doaj.art-5ee3dfa097dc4ed9a000f1247049f819 |
| institution | Directory Open Access Journal |
| issn | 2175-8239 |
| language | English |
| last_indexed | 2024-12-24T01:52:47Z |
| publishDate | 2020-08-01 |
| publisher | Sociedade Brasileira de Nefrologia |
| record_format | Article |
| series | Brazilian Journal of Nephrology |
| spelling | doaj.art-5ee3dfa097dc4ed9a000f1247049f8192022-12-21T17:21:40ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-82392020-08-0142448448810.1590/2175-8239-jbn-2019-0229Idiopathic nodular glomerulosclerosis and differential diagnosisSergio Raúl Alvizures Solareshttps://orcid.org/0000-0003-0810-1853Héctor Raúl Ibarra-Sifuenteshttps://orcid.org/0000-0002-7258-360XMaría Guadalupe Ramírez Ramírezhttps://orcid.org/0000-0002-7909-5457Giovanna Yazmin Arteaga Mullerhttps://orcid.org/0000-0002-9617-6128Jesús Cruz Valdezhttps://orcid.org/0000-0003-0916-6464ABSTRACT Introduction: Idiopathic nodular glomerulosclerosis (ING) is a condition that has a vasculopathic glomerular histological pattern. Case presentation: The authors present the case of a 44-year-old Hispanic smoker female with hypertension and peripheral arterial disease who presented nephrotic syndrome for 2 weeks. The patient was diagnosed with ING by percutaneous renal biopsy results, which showed global nodular mesangial matrix expansion, with linear staining accentuation of glomerular and tubular basement membrane for Immunoglobulin G (IgG) and albumin on immunofluorescence. Conclusions: ING is a rare disease with a poor renal prognosis and wide diagnostic approach; we highlight the importance of analyzing every piece of detail together to reach a definitive diagnosis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400484&tlng=enDiabetic NephropathiesBiopsyHypertensionTobacco Use Disorder |
| spellingShingle | Sergio Raúl Alvizures Solares Héctor Raúl Ibarra-Sifuentes María Guadalupe Ramírez Ramírez Giovanna Yazmin Arteaga Muller Jesús Cruz Valdez Idiopathic nodular glomerulosclerosis and differential diagnosis Brazilian Journal of Nephrology Diabetic Nephropathies Biopsy Hypertension Tobacco Use Disorder |
| title | Idiopathic nodular glomerulosclerosis and differential diagnosis |
| title_full | Idiopathic nodular glomerulosclerosis and differential diagnosis |
| title_fullStr | Idiopathic nodular glomerulosclerosis and differential diagnosis |
| title_full_unstemmed | Idiopathic nodular glomerulosclerosis and differential diagnosis |
| title_short | Idiopathic nodular glomerulosclerosis and differential diagnosis |
| title_sort | idiopathic nodular glomerulosclerosis and differential diagnosis |
| topic | Diabetic Nephropathies Biopsy Hypertension Tobacco Use Disorder |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002020000400484&tlng=en |
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