Intra-Articular Hyaluronic Acid and Chondroitin Sulfate: Pharmacokinetic Investigation in Osteoarthritic Rat Models

Intra-Articular Hyaluronic Acid and Chondroitin Sulfate: Pharmacokinetic Investigation in Osteoarthritic Rat Models

ABSTRACT: Background: Viscosupplementation of synovial fluid with intra-articular (IA) injections of hyaluronic acid (HA) is widely used for symptomatic treatment of osteoarthritis (OA). Herein we present HCS, a new combination of chemicals, associating HA and chondroitin sulfate (CS), both members...

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Bibliographic Details
Main Authors:	Massimiliano Fonsi, PhD, MSc, Abdel-Ilah El Amrani, PhD, Frédéric Gervais, DVM, ECVP, Patrice Vincent, MEng
Format:	Article
Language:	English
Published:	Elsevier 2020-01-01
Series:	Current Therapeutic Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0011393X19300220

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