App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial
This study aims to assess the effect of an increase in daily physical activity to prevent cognitive decline, sustain brain volumes and maintain healthy biomarker levels in previously inactive (< 7,000 steps/day) mild cognitive impairment (MCI) subjects aged 50-65 years. In total, 198 subjects wit...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Poznan University of Medical Sciences
2021-09-01
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| Series: | Journal of Medical Science |
| Subjects: | |
| Online Access: | https://jms.ump.edu.pl/index.php/JMS/article/view/530 |
| _version_ | 1798022988129370112 |
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| author | Małgorzata Jamka Aleksandra Makarewicz Maria Wasiewicz-Gajdzis Jan Brylak Hanna Wielińska-Wiśniewska Zuzanna Pawlak Jan Krzysztof Nowak Karl-Heinz Herzig Edyta Mądry Jarosław Walkowiak |
| author_facet | Małgorzata Jamka Aleksandra Makarewicz Maria Wasiewicz-Gajdzis Jan Brylak Hanna Wielińska-Wiśniewska Zuzanna Pawlak Jan Krzysztof Nowak Karl-Heinz Herzig Edyta Mądry Jarosław Walkowiak |
| author_sort | Małgorzata Jamka |
| collection | DOAJ |
| description | This study aims to assess the effect of an increase in daily physical activity to prevent cognitive decline, sustain brain volumes and maintain healthy biomarker levels in previously inactive (< 7,000 steps/day) mild cognitive impairment (MCI) subjects aged 50-65 years. In total, 198 subjects with MCI (assessed using the Montreal Cognitive Assessment test) will be recruited and randomised into two groups: active and passive. The active group will be instructed, encouraged and motivated to increase their physical activity to a moderate level (≥ 10,000 steps/day), while the passive group should maintain their normal activity levels. All subjects will undergo cognitive assessment, neuroimaging and biomarker tests before and after a one-year intervention. During the intervention, physical activity will be measured by the Fitbit Inspire HR wristband. The study was registered in the German Clinical Trials Register database (registration no. DRKS00020943, date of registration: 09.03.2020, protocol version: 1.0). |
| first_indexed | 2024-04-11T17:38:52Z |
| format | Article |
| id | doaj.art-5ee5a69b754f4d85b36e53e311bab7db |
| institution | Directory Open Access Journal |
| issn | 2353-9798 2353-9801 |
| language | English |
| last_indexed | 2024-04-11T17:38:52Z |
| publishDate | 2021-09-01 |
| publisher | Poznan University of Medical Sciences |
| record_format | Article |
| series | Journal of Medical Science |
| spelling | doaj.art-5ee5a69b754f4d85b36e53e311bab7db2022-12-22T04:11:33ZengPoznan University of Medical SciencesJournal of Medical Science2353-97982353-98012021-09-0110.20883/medical.e530App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trialMałgorzata Jamka0Aleksandra Makarewicz1Maria Wasiewicz-Gajdzis2Jan Brylak3Hanna Wielińska-Wiśniewska4Zuzanna Pawlak5Jan Krzysztof Nowak6Karl-Heinz Herzig7Edyta Mądry8Jarosław Walkowiak9Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, Poland1Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, Poland & Research Unit of Biomedicine, University of Oulu, Oulu, FinlandDepartment of Physiology, Poznan University of Medical Sciences, Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznań, PolandThis study aims to assess the effect of an increase in daily physical activity to prevent cognitive decline, sustain brain volumes and maintain healthy biomarker levels in previously inactive (< 7,000 steps/day) mild cognitive impairment (MCI) subjects aged 50-65 years. In total, 198 subjects with MCI (assessed using the Montreal Cognitive Assessment test) will be recruited and randomised into two groups: active and passive. The active group will be instructed, encouraged and motivated to increase their physical activity to a moderate level (≥ 10,000 steps/day), while the passive group should maintain their normal activity levels. All subjects will undergo cognitive assessment, neuroimaging and biomarker tests before and after a one-year intervention. During the intervention, physical activity will be measured by the Fitbit Inspire HR wristband. The study was registered in the German Clinical Trials Register database (registration no. DRKS00020943, date of registration: 09.03.2020, protocol version: 1.0).https://jms.ump.edu.pl/index.php/JMS/article/view/530physical activitycognitive functionsmild cognitive impairment |
| spellingShingle | Małgorzata Jamka Aleksandra Makarewicz Maria Wasiewicz-Gajdzis Jan Brylak Hanna Wielińska-Wiśniewska Zuzanna Pawlak Jan Krzysztof Nowak Karl-Heinz Herzig Edyta Mądry Jarosław Walkowiak App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial Journal of Medical Science physical activity cognitive functions mild cognitive impairment |
| title | App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial |
| title_full | App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial |
| title_fullStr | App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial |
| title_full_unstemmed | App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial |
| title_short | App-assured essential physical activity for the prevention of cognitive decline: changing paradigms in public health – a study protocol for a randomised controlled trial |
| title_sort | app assured essential physical activity for the prevention of cognitive decline changing paradigms in public health a study protocol for a randomised controlled trial |
| topic | physical activity cognitive functions mild cognitive impairment |
| url | https://jms.ump.edu.pl/index.php/JMS/article/view/530 |
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