Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study
Abstract Background and aims The older people bears a severe burden of disease due to frailty and depressive symptoms, however, the results of association between the two in the older Chinese people have been conflicting. Therefore, this study aimed to investigate the developmental trajectories and...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-024-17824-3 |
| _version_ | 1827328880319397888 |
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| author | Ni Sang Rong-chao Liu Ming-hui Zhang Zong-Xiao Lu Zhen-Gang Wu Meng-Yao Zhang Bo-Han Li Meng Wei Hai-Feng Pan Guo Cui Wu |
| author_facet | Ni Sang Rong-chao Liu Ming-hui Zhang Zong-Xiao Lu Zhen-Gang Wu Meng-Yao Zhang Bo-Han Li Meng Wei Hai-Feng Pan Guo Cui Wu |
| author_sort | Ni Sang |
| collection | DOAJ |
| description | Abstract Background and aims The older people bears a severe burden of disease due to frailty and depressive symptoms, however, the results of association between the two in the older Chinese people have been conflicting. Therefore, this study aimed to investigate the developmental trajectories and interactions of frailty and depressive symptoms in the Chinese middle-aged and older adults. Methods The study used four waves of data from 2011, 2013, 2015 and 2018 in the China Health and Retirement Longitudinal Study (CHARLS) database, focused on middle-aged and older people ≥ 45 years of age, and analyzed using latent growth models and cross-lagged models. Results The parallel latent growth model showed that the initial level of depressive symptoms had a significant positive predictive effect on the initial level of frailty. The rate of change in depressive symptoms significantly positively predicted the rate of change in frailty. The initial level of frailty had a significant positive predictive effect on the initial level of depressive symptoms, but a significant negative predictive effect on the rate of change in depressive symptoms. The rate of change in frailty had a significant positive predictive effect on the rate of change in depressive symptoms. The results of the cross-lagged analysis indicated a bidirectional causal association between frailty and depressive symptoms in the total sample population. Results for the total sample population grouped by age and gender were consistent with the total sample. Conclusions This study recommends advancing the age of concern for frailty and depressive symptoms to middle-aged adults. Both men and women need early screening and intervention for frailty and depressive symptoms to promote healthy aging. |
| first_indexed | 2024-03-07T15:24:45Z |
| format | Article |
| id | doaj.art-5ee658435e5b48a1b1f5d6e76acfc77c |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-03-07T15:24:45Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-5ee658435e5b48a1b1f5d6e76acfc77c2024-03-05T17:08:26ZengBMCBMC Public Health1471-24582024-01-0124111310.1186/s12889-024-17824-3Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort studyNi Sang0Rong-chao Liu1Ming-hui Zhang2Zong-Xiao Lu3Zhen-Gang Wu4Meng-Yao Zhang5Bo-Han Li6Meng Wei7Hai-Feng Pan8Guo Cui Wu9School of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversitySchool of Nursing, Anhui Medical UniversityInflammation and Immune Mediated Diseases Laboratory of Anhui ProvinceSchool of Nursing, Anhui Medical UniversityAbstract Background and aims The older people bears a severe burden of disease due to frailty and depressive symptoms, however, the results of association between the two in the older Chinese people have been conflicting. Therefore, this study aimed to investigate the developmental trajectories and interactions of frailty and depressive symptoms in the Chinese middle-aged and older adults. Methods The study used four waves of data from 2011, 2013, 2015 and 2018 in the China Health and Retirement Longitudinal Study (CHARLS) database, focused on middle-aged and older people ≥ 45 years of age, and analyzed using latent growth models and cross-lagged models. Results The parallel latent growth model showed that the initial level of depressive symptoms had a significant positive predictive effect on the initial level of frailty. The rate of change in depressive symptoms significantly positively predicted the rate of change in frailty. The initial level of frailty had a significant positive predictive effect on the initial level of depressive symptoms, but a significant negative predictive effect on the rate of change in depressive symptoms. The rate of change in frailty had a significant positive predictive effect on the rate of change in depressive symptoms. The results of the cross-lagged analysis indicated a bidirectional causal association between frailty and depressive symptoms in the total sample population. Results for the total sample population grouped by age and gender were consistent with the total sample. Conclusions This study recommends advancing the age of concern for frailty and depressive symptoms to middle-aged adults. Both men and women need early screening and intervention for frailty and depressive symptoms to promote healthy aging.https://doi.org/10.1186/s12889-024-17824-3FrailtyDepressive symptomsChinese middle-aged and older adultsCHARLS |
| spellingShingle | Ni Sang Rong-chao Liu Ming-hui Zhang Zong-Xiao Lu Zhen-Gang Wu Meng-Yao Zhang Bo-Han Li Meng Wei Hai-Feng Pan Guo Cui Wu Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study BMC Public Health Frailty Depressive symptoms Chinese middle-aged and older adults CHARLS |
| title | Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study |
| title_full | Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study |
| title_fullStr | Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study |
| title_full_unstemmed | Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study |
| title_short | Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study |
| title_sort | changes in frailty and depressive symptoms among middle aged and older chinese people a nationwide cohort study |
| topic | Frailty Depressive symptoms Chinese middle-aged and older adults CHARLS |
| url | https://doi.org/10.1186/s12889-024-17824-3 |
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