SGLT2 Inhibition on Cardiac Mitochondrial Function: Searching for a Sweet Spot

SGLT2 Inhibition on Cardiac Mitochondrial Function: Searching for a Sweet Spot

Bibliographic Details
Main Authors:	Konrad Teodor Sawicki, Issam Ben‐Sahra, Elizabeth M. McNally
Format:	Article
Language:	English
Published:	Wiley 2021-07-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:	Editorials cardiomyopathy diabetic cardiomyopathy heart (diabetes mellitus) metabolism mitochondria
Online Access:	https://www.ahajournals.org/doi/10.1161/JAHA.121.021949

Similar Items

Mitochondrial Mechanisms in Diabetic Cardiomyopathy
by: Johannes Gollmer, et al.
Published: (2020-02-01)

PACS2/CPT1A/DHODH signaling promotes cardiomyocyte ferroptosis in diabetic cardiomyopathy
by: Hong Xiang, et al.
Published: (2024-12-01)

Beta-adrenergic agonism protects mitochondrial metabolism in the pancreatectomised rat heart
by: Ross T. Lindsay, et al.
Published: (2024-08-01)

Effect of exercise on improving myocardial mitochondrial function in decreasing diabetic cardiomyopathy
by: Feng Zhang, et al.
Published: (2024-02-01)

Echocardiographic Changes in Saudi Patients with Type 2 Diabetes Mellitus
by: Turky H. Almigbal, et al.
Published: (2023-11-01)

SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM
by: Pankaj K. Bagul, et al.
Published: (2018-11-01)

Exercise Augments the Effect of SGLT2 Inhibitor Dapagliflozin on Experimentally Induced Diabetic Cardiomyopathy, Possible Underlying Mechanisms
by: Mamdouh Eldesoqui, et al.
Published: (2022-07-01)

Mitochondrial ROS Formation in the Pathogenesis of Diabetic Cardiomyopathy
by: Nina Kaludercic, et al.
Published: (2020-02-01)

Diabetıc Cardiomyopathy And G Protein
by: Yasemin Behram Kandemir, et al.
Published: (2019-07-01)

The Effects of Hesperidin, on Cardiac Dysfunction of Experimental Type-I Diabetic Rats
by: A Kouhpayeh, et al.
Published: (2009-04-01)

Sustained Increases in Cardiomyocyte Protein O‐Linked β‐N‐Acetylglucosamine Levels Lead to Cardiac Hypertrophy and Reduced Mitochondrial Function Without Systolic Contractile Impairment
by: Chae‐Myeong Ha, et al.
Published: (2023-10-01)

SGLT2 Inhibitors: A Novel Player in the Treatment and Prevention of Diabetic Cardiomyopathy
by: Li N, et al.
Published: (2020-11-01)

Heart failure and diabetes mellitus: insight into comorbidity
by: Nina A. Petunina, et al.
Published: (2019-03-01)

Effect of extruded djulis (Chenopodium formosanum) snacks on the ameliorative potential against diabetic cardiomyopathy
by: Yu-Tsung Cheng, et al.
Published: (2024-05-01)

Diabetic cardiomyopathy: a brief summary on lipid toxicity
by: Jiahan Ke, et al.
Published: (2023-04-01)

Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis
by: Cheng Peng, et al.
Published: (2023-02-01)

Ferroptosis in diabetic cardiomyopathy: from its mechanisms to therapeutic strategies
by: Meimei Tian, et al.
Published: (2024-11-01)

Deletion of MAPL ameliorates septic cardiomyopathy by mitigating mitochondrial dysfunction
by: Yinghua Wang, et al.
Published: (2024-11-01)

The impact of diabetes mellitus on cardiac function assessed by magnetic resonance imaging in patients with hypertrophic cardiomyopathy
by: Shi-Qin Yu, et al.
Published: (2024-08-01)

The double burden: type 1 diabetes and heart failure—a comprehensive review
by: María Teresa Julián, et al.
Published: (2024-02-01)

Uncontrolled diabetes resulting in diabetic cardiomyopathy in a young male patient and eventually presenting with a stroke
by: Konstantinos Kritikos, et al.
Published: (2014-01-01)

Cardiac Dysfunction in Early Stages of Diabetic Kidney Disease- Fact or Fiction: A Case-control Study
by: Richard Bruno Michael, et al.
Published: (2022-12-01)

Insights into SGLT2 inhibitor treatment of diabetic cardiomyopathy: focus on the mechanisms
by: Keming Huang, et al.
Published: (2023-04-01)

Diabetic cardiomyopathy: pathophysiology, imaging assessment and therapeutical strategies
by: Vincenzo Rizza, et al.
Published: (2024-12-01)

Update on clinical and experimental management of diabetic cardiomyopathy: addressing current and future therapy
by: Peter Galis, et al.
Published: (2024-07-01)

Curcumin, A Polyphenolic Curcuminoid With Its Protective Effects and Molecular Mechanisms in Diabetes and Diabetic Cardiomyopathy
by: Jia Zheng, et al.
Published: (2018-05-01)

High glucose affects the cardiac function of diabetic Akita mice by inhibiting cardiac ATP synthase beta subunit
by: Yuanfang Ma, et al.
Published: (2025-03-01)

The Importance of SGLT-2 Inhibitors as Both the Prevention and the Treatment of Diabetic Cardiomyopathy
by: Klaudia Kowalska, et al.
Published: (2022-12-01)

Exploring the role of metabolism in cancer and cardiac settings
by: Carter, RD
Published: (2024)

Adenosine monophosphate deaminase in the endoplasmic reticulum–mitochondria interface promotes mitochondrial Ca2+ overload in type 2 diabetes rat hearts
by: Arata Osanami, et al.
Published: (2023-04-01)

Assessment of left ventricular functions in patients with type 2 diabetes mellitus using tissue Doppler imaging and its correlation with a novel cardiac biomarker
by: Ebtissam Zakria, et al.
Published: (2017-01-01)

Panax notoginseng Saponin Protects Against Diabetic Cardiomyopathy Through Lipid Metabolism Modulation
by: Chenyang Zhang, et al.
Published: (2022-02-01)

Editorial: Understanding Molecular Mechanisms in Diabetic Cardiomyopathy (DCM)
by: Sakthijothi Muthu, et al.
Published: (2022-06-01)

Lipotoxicity as a therapeutic target in obesity and diabetic cardiomyopathy
by: Michinari Nakamura
Published: (2024-04-01)

Research status and trends of the diabetic cardiomyopathy in the past 10 years (2012–2021): A bibliometric analysis
by: Sicheng Wang, et al.
Published: (2022-10-01)

Diabetes without Overt Cardiac Disease Is Associated with Markers of Abnormal Repolarization: A Case-Control Study
by: Tomer Stahi, et al.
Published: (2022-07-01)

Multi-omics insights into potential mechanism of SGLT2 inhibitors cardiovascular benefit in diabetic cardiomyopathy
by: Yangbo Xi, et al.
Published: (2022-10-01)

Association of Diabetes Mellitus on Cardiac Remodeling, Quality of Life, and Clinical Outcomes in Heart Failure With Reduced and Preserved Ejection Fraction
by: Jonathan Yap, et al.
Published: (2019-09-01)

Research progress on the mitochondrial translocation and degradation
by: WANG Meng-yi, LI Qian-zhu, ZHANG Shi-wu, SHU Feng, ZHANG Wei-hua
Published: (2021-10-01)

SGLT2 inhibitors: a new pillar of the heart failure regimen
by: Travis DeSa, et al.
Published: (2021-12-01)