2D Material‐Based Optical Biosensor: Status and Prospect

Abstract The combination of 2D materials and optical biosensors has become a hot research topic in recent years. Graphene, transition metal dichalcogenides, black phosphorus, MXenes, and other 2D materials (metal oxides and degenerate semiconductors) have unique optical properties and play a unique...

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Main Authors: Zong‐Lin Lei, Bo Guo
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202102924
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author Zong‐Lin Lei
Bo Guo
author_facet Zong‐Lin Lei
Bo Guo
author_sort Zong‐Lin Lei
collection DOAJ
description Abstract The combination of 2D materials and optical biosensors has become a hot research topic in recent years. Graphene, transition metal dichalcogenides, black phosphorus, MXenes, and other 2D materials (metal oxides and degenerate semiconductors) have unique optical properties and play a unique role in the detection of different biomolecules. Through the modification of 2D materials, optical biosensor has the advantages that traditional sensors (such as electrical sensing) do not have, and the sensitivity and detection limit are greatly improved. Here, optical biosensors based on different 2D materials are reviewed. First, various detection methods of biomolecules, including surface plasmon resonance (SPR), fluorescence resonance energy transfer (FRET), and evanescent wave and properties, preparation and integration strategies of 2D material, are introduced in detail. Second, various biosensors based on 2D materials are summarized. Furthermore, the applications of these optical biosensors in biological imaging, food safety, pollution prevention/control, and biological medicine are discussed. Finally, the future development of optical biosensors is prospected. It is believed that with their in‐depth research in the laboratory, optical biosensors will gradually become commercialized and improve people's quality of life in many aspects.
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spelling doaj.art-5ee92ae9e87644358af0d8228e0da3912022-12-21T23:49:12ZengWileyAdvanced Science2198-38442022-02-0194n/an/a10.1002/advs.2021029242D Material‐Based Optical Biosensor: Status and ProspectZong‐Lin Lei0Bo Guo1Key Lab of In‐Fiber Integrated Optics of Ministry of Education of China Harbin Engineering University Harbin 150001 ChinaKey Lab of In‐Fiber Integrated Optics of Ministry of Education of China Harbin Engineering University Harbin 150001 ChinaAbstract The combination of 2D materials and optical biosensors has become a hot research topic in recent years. Graphene, transition metal dichalcogenides, black phosphorus, MXenes, and other 2D materials (metal oxides and degenerate semiconductors) have unique optical properties and play a unique role in the detection of different biomolecules. Through the modification of 2D materials, optical biosensor has the advantages that traditional sensors (such as electrical sensing) do not have, and the sensitivity and detection limit are greatly improved. Here, optical biosensors based on different 2D materials are reviewed. First, various detection methods of biomolecules, including surface plasmon resonance (SPR), fluorescence resonance energy transfer (FRET), and evanescent wave and properties, preparation and integration strategies of 2D material, are introduced in detail. Second, various biosensors based on 2D materials are summarized. Furthermore, the applications of these optical biosensors in biological imaging, food safety, pollution prevention/control, and biological medicine are discussed. Finally, the future development of optical biosensors is prospected. It is believed that with their in‐depth research in the laboratory, optical biosensors will gradually become commercialized and improve people's quality of life in many aspects.https://doi.org/10.1002/advs.2021029242D materialsevanescent wavefluorescence resonance energy transferoptical biosensorsurface plasmon resonance
spellingShingle Zong‐Lin Lei
Bo Guo
2D Material‐Based Optical Biosensor: Status and Prospect
Advanced Science
2D materials
evanescent wave
fluorescence resonance energy transfer
optical biosensor
surface plasmon resonance
title 2D Material‐Based Optical Biosensor: Status and Prospect
title_full 2D Material‐Based Optical Biosensor: Status and Prospect
title_fullStr 2D Material‐Based Optical Biosensor: Status and Prospect
title_full_unstemmed 2D Material‐Based Optical Biosensor: Status and Prospect
title_short 2D Material‐Based Optical Biosensor: Status and Prospect
title_sort 2d material based optical biosensor status and prospect
topic 2D materials
evanescent wave
fluorescence resonance energy transfer
optical biosensor
surface plasmon resonance
url https://doi.org/10.1002/advs.202102924
work_keys_str_mv AT zonglinlei 2dmaterialbasedopticalbiosensorstatusandprospect
AT boguo 2dmaterialbasedopticalbiosensorstatusandprospect