Myostatin Mutation Enhances Bovine Myogenic Differentiation through PI3K/AKT/mTOR Signalling via Removing DNA Methylation of RACK1

Myostatin Mutation Enhances Bovine Myogenic Differentiation through PI3K/AKT/mTOR Signalling via Removing DNA Methylation of RACK1

Myostatin (MSTN) is a negative regulator of skeletal muscle development and plays an important role in muscle development. Fluctuations in gene expression influenced by DNA methylation are critical for homeostatic responses in muscle. However, little is known about the mechanisms underlying this flu...

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Bibliographic Details
Main Authors: Yiping Zhao, Xiaoxia Xia, Qiaomeng Wang, Debao Hu, Linlin Zhang, Xin Li, Xiangbin Ding, Hong Guo, Yiwen Guo
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
myostatin
DNA methylation
RACK1
PI3K/AKT/mTOR signaling
myogenic differentiation
Online Access:https://www.mdpi.com/2073-4409/12/1/59

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