Redrawing Urokinase Receptor (uPAR) Signaling with Cancer Driver Genes for Exploring Possible Anti-Cancer Targets and Drugs

Redrawing Urokinase Receptor (uPAR) Signaling with Cancer Driver Genes for Exploring Possible Anti-Cancer Targets and Drugs

During tumorigenesis, urokinase (uPA) and uPA receptor (uPAR) play essential roles in mediating pathological progression in many cancers. To understand the crosstalk between the uPA/uPAR signaling and cancer, as well as to decipher their cellular pathways, we proposed to use cancer driver genes to m...

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Bibliographic Details
Main Authors:	Yu-Ching Chang, Chung-Ze Wu, Chao-Wen Cheng, Jin-Shuen Chen, Li-Chien Chang
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Series:	Pharmaceuticals
Subjects:	uPAR-mediated signaling system cancer driver gene network analysis uPAR modulator a pharmaceutical bioinformatics study
Online Access:	https://www.mdpi.com/1424-8247/16/10/1435

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