Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment
<p>Abstract</p> <p>Background</p> <p>The search for naturally occurring nanocomposites with diverse properties for tissue engineering has been a major interest for biomaterial research. In this study, we investigated a nanofiber and nanoparticle based nanocomposite secr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-08-01
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| Series: | Journal of Nanobiotechnology |
| Online Access: | http://www.jnanobiotechnology.com/content/8/1/20 |
| _version_ | 1798042121478864896 |
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| author | Zhang Mingjun Lenaghan Scott C Xia Lijin Dong Lixin He Wei Henson William R Fan Xudong |
| author_facet | Zhang Mingjun Lenaghan Scott C Xia Lijin Dong Lixin He Wei Henson William R Fan Xudong |
| author_sort | Zhang Mingjun |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The search for naturally occurring nanocomposites with diverse properties for tissue engineering has been a major interest for biomaterial research. In this study, we investigated a nanofiber and nanoparticle based nanocomposite secreted from an insect-capturing plant, the Sundew, for cell attachment. The adhesive nanocomposite has demonstrated high biocompatibility and is ready to be used with minimal preparation.</p> <p>Results</p> <p>Atomic force microscopy (AFM) conducted on the adhesive from three species of Sundew found that a network of nanofibers and nanoparticles with various sizes existed independent of the coated surface. AFM and light microscopy confirmed that the pattern of nanofibers corresponded to Alcian Blue staining for polysaccharide. Transmission electron microscopy identified a low abundance of nanoparticles in different pattern form AFM observations. In addition, energy-dispersive X-ray spectroscopy revealed the presence of Ca, Mg, and Cl, common components of biological salts. Study of the material properties of the adhesive yielded high viscoelasticity from the liquid adhesive, with reduced elasticity observed in the dried adhesive. The ability of PC12 neuron-like cells to attach and grow on the network of nanofibers created from the dried adhesive demonstrated the potential of this network to be used in tissue engineering, and other biomedical applications.</p> <p>Conclusions</p> <p>This discovery demonstrates how a naturally occurring nanofiber and nanoparticle based nanocomposite from the adhesive of Sundew can be used for tissue engineering, and opens the possibility for further examination of natural plant adhesives for biomedical applications.</p> |
| first_indexed | 2024-04-11T22:31:07Z |
| format | Article |
| id | doaj.art-5ef3b7bba0e44026aec1f9eaed63abfa |
| institution | Directory Open Access Journal |
| issn | 1477-3155 |
| language | English |
| last_indexed | 2024-04-11T22:31:07Z |
| publishDate | 2010-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Nanobiotechnology |
| spelling | doaj.art-5ef3b7bba0e44026aec1f9eaed63abfa2022-12-22T03:59:23ZengBMCJournal of Nanobiotechnology1477-31552010-08-01812010.1186/1477-3155-8-20Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachmentZhang MingjunLenaghan Scott CXia LijinDong LixinHe WeiHenson William RFan Xudong<p>Abstract</p> <p>Background</p> <p>The search for naturally occurring nanocomposites with diverse properties for tissue engineering has been a major interest for biomaterial research. In this study, we investigated a nanofiber and nanoparticle based nanocomposite secreted from an insect-capturing plant, the Sundew, for cell attachment. The adhesive nanocomposite has demonstrated high biocompatibility and is ready to be used with minimal preparation.</p> <p>Results</p> <p>Atomic force microscopy (AFM) conducted on the adhesive from three species of Sundew found that a network of nanofibers and nanoparticles with various sizes existed independent of the coated surface. AFM and light microscopy confirmed that the pattern of nanofibers corresponded to Alcian Blue staining for polysaccharide. Transmission electron microscopy identified a low abundance of nanoparticles in different pattern form AFM observations. In addition, energy-dispersive X-ray spectroscopy revealed the presence of Ca, Mg, and Cl, common components of biological salts. Study of the material properties of the adhesive yielded high viscoelasticity from the liquid adhesive, with reduced elasticity observed in the dried adhesive. The ability of PC12 neuron-like cells to attach and grow on the network of nanofibers created from the dried adhesive demonstrated the potential of this network to be used in tissue engineering, and other biomedical applications.</p> <p>Conclusions</p> <p>This discovery demonstrates how a naturally occurring nanofiber and nanoparticle based nanocomposite from the adhesive of Sundew can be used for tissue engineering, and opens the possibility for further examination of natural plant adhesives for biomedical applications.</p>http://www.jnanobiotechnology.com/content/8/1/20 |
| spellingShingle | Zhang Mingjun Lenaghan Scott C Xia Lijin Dong Lixin He Wei Henson William R Fan Xudong Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment Journal of Nanobiotechnology |
| title | Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment |
| title_full | Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment |
| title_fullStr | Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment |
| title_full_unstemmed | Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment |
| title_short | Nanofibers and nanoparticles from the insect-capturing adhesive of the Sundew (<it>Drosera</it>) for cell attachment |
| title_sort | nanofibers and nanoparticles from the insect capturing adhesive of the sundew it drosera it for cell attachment |
| url | http://www.jnanobiotechnology.com/content/8/1/20 |
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