Cross-talks between the kidneys and the central nervous system in multiple sclerosis
Multiple sclerosis (MS) is an inflammatory demyelinating disease, which is considered as a common autoimmune disorder in young adults. A growing number of evidences indicated that the impairment in non-neural tissues plays a significant role in pathology of MS disease. There are bidirectional relati...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2018-05-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/browse.php?a_code=A-10-836-1&slc_lang=en&sid=1 |
| _version_ | 1818040454090850304 |
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| author | Sahar Rostami Mohammad Sajad Emami Aleagha Maryam Ghasemi-Kasman Abdolamir Allameh |
| author_facet | Sahar Rostami Mohammad Sajad Emami Aleagha Maryam Ghasemi-Kasman Abdolamir Allameh |
| author_sort | Sahar Rostami |
| collection | DOAJ |
| description | Multiple sclerosis (MS) is an inflammatory demyelinating disease, which is considered as a common autoimmune disorder in young adults. A growing number of evidences indicated that the impairment in non-neural tissues plays a significant role in pathology of MS disease. There are bidirectional relationship, metabolic activities and functional similarity between central nervous system (CNS) and kidneys which suggest that kidney tissue may exert remarkable effects on some aspects of MS disorder and CNS impairment in these patients compels the kidney to respond to central inflammation. Recently, it has been well documented that hormonal secretion possesses the important role on CNS abnormalities. In this regard, due to the functional similarity and significant hormonal and non-hormonal relationship between CNS and kidneys, we hypothesized that kidneys exert significant effect on initiation, progression or amelioration of MS disease which might be regarded as potential therapeutic approach in the treatment of MS patients in the future. |
| first_indexed | 2024-12-10T08:14:47Z |
| format | Article |
| id | doaj.art-5efa734afc6e4eb3b2f6c34f16364720 |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-12-10T08:14:47Z |
| publishDate | 2018-05-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-5efa734afc6e4eb3b2f6c34f163647202022-12-22T01:56:29ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722018-05-0193206210Cross-talks between the kidneys and the central nervous system in multiple sclerosisSahar Rostami0Mohammad Sajad Emami Aleagha1Maryam Ghasemi-Kasman2Abdolamir Allameh3 Department of Clinical Biochemistry, Faculty of Medicine, Tarbiat Modarres University, Tehran, Iran Department of Clinical Biochemistry, Faculty of Medicine, Tarbiat Modarres University, Tehran, Iran Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Department of Clinical Biochemistry, Faculty of Medicine, Tarbiat Modarres University, Tehran, Iran Multiple sclerosis (MS) is an inflammatory demyelinating disease, which is considered as a common autoimmune disorder in young adults. A growing number of evidences indicated that the impairment in non-neural tissues plays a significant role in pathology of MS disease. There are bidirectional relationship, metabolic activities and functional similarity between central nervous system (CNS) and kidneys which suggest that kidney tissue may exert remarkable effects on some aspects of MS disorder and CNS impairment in these patients compels the kidney to respond to central inflammation. Recently, it has been well documented that hormonal secretion possesses the important role on CNS abnormalities. In this regard, due to the functional similarity and significant hormonal and non-hormonal relationship between CNS and kidneys, we hypothesized that kidneys exert significant effect on initiation, progression or amelioration of MS disease which might be regarded as potential therapeutic approach in the treatment of MS patients in the future.http://caspjim.com/browse.php?a_code=A-10-836-1&slc_lang=en&sid=1Multiple sclerosis Kidneys Central nervous system Hormones |
| spellingShingle | Sahar Rostami Mohammad Sajad Emami Aleagha Maryam Ghasemi-Kasman Abdolamir Allameh Cross-talks between the kidneys and the central nervous system in multiple sclerosis Caspian Journal of Internal Medicine Multiple sclerosis Kidneys Central nervous system Hormones |
| title | Cross-talks between the kidneys and the central nervous system in multiple sclerosis |
| title_full | Cross-talks between the kidneys and the central nervous system in multiple sclerosis |
| title_fullStr | Cross-talks between the kidneys and the central nervous system in multiple sclerosis |
| title_full_unstemmed | Cross-talks between the kidneys and the central nervous system in multiple sclerosis |
| title_short | Cross-talks between the kidneys and the central nervous system in multiple sclerosis |
| title_sort | cross talks between the kidneys and the central nervous system in multiple sclerosis |
| topic | Multiple sclerosis Kidneys Central nervous system Hormones |
| url | http://caspjim.com/browse.php?a_code=A-10-836-1&slc_lang=en&sid=1 |
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