Assessment of the antidepressant effect of caffeine using rat model of depression induced by reserpine

Assessment of the antidepressant effect of caffeine using rat model of depression induced by reserpine

Abstract Objective The present objective is to evaluate the antidepressant activity of caffeine. Material and methods Three groups of rats were used; control, reserpine-induced rat model of depression, and rat model of depression treated daily with caffeine. At the end of the experiment, the motor a...

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Bibliographic Details
Main Authors: Yasser A. Khadrawy, Hussein G. Sawie, Eman N. Hosny, Hagar H. Mourad
Format: Article
Language:English
Published: SpringerOpen 2018-12-01
Series:Bulletin of the National Research Centre
Subjects:
Depression
Caffeine
Monoamines
Oxidative stress
Acetylcholinesterase
Online Access:http://link.springer.com/article/10.1186/s42269-018-0034-1

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