The role of GABA in islet function

Gamma aminobutyric acid (GABA) is a non-proteinogenic amino acid and neurotransmitter that is produced in the islet at levels as high as in the brain. GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD), of which the 65 kDa isoform (GAD65) is a major autoantigen in type 1 diabetes. O...

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Podrobná bibliografie
Hlavní autoři: D. Walker Hagan, Sandra M. Ferreira, Gustavo J. Santos, Edward A. Phelps
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2022-09-01
Edice:Frontiers in Endocrinology
Témata:
On-line přístup:https://www.frontiersin.org/articles/10.3389/fendo.2022.972115/full