The role of GABA in islet function

Gamma aminobutyric acid (GABA) is a non-proteinogenic amino acid and neurotransmitter that is produced in the islet at levels as high as in the brain. GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD), of which the 65 kDa isoform (GAD65) is a major autoantigen in type 1 diabetes. O...

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书目详细资料
Main Authors: D. Walker Hagan, Sandra M. Ferreira, Gustavo J. Santos, Edward A. Phelps
格式: 文件
语言:English
出版: Frontiers Media S.A. 2022-09-01
丛编:Frontiers in Endocrinology
主题:
在线阅读:https://www.frontiersin.org/articles/10.3389/fendo.2022.972115/full