Ugonin L inhibits osteoclast formation and promotes osteoclast apoptosis by inhibiting the MAPK and NF-κB pathways

Ugonin L inhibits osteoclast formation and promotes osteoclast apoptosis by inhibiting the MAPK and NF-κB pathways

Bone loss is a major issue for patients with osteoporosis, arthritis, periodontitis, and bone metastasis; however, anti-resorption drugs used to treat bone loss have been linked to a variety of adverse effects. Helminthostachys zeylanica (L.) Hook, belonging to the family Ophioglossaceae, is commonl...

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Bibliographic Details
Main Authors: Chun-Lin Liu, Trung-Loc Ho, Shuen-Yih Fang, Jeng-Hung Guo, Chih-Ying Wu, Yi-Chin Fong, Chih-Chuang Liaw, Chih-Hsin Tang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ugonin L
Osteoclast
RANKL
Bone resorption
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223011903

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